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- 2025年11月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
蛋白表达区间:Cys24-Gly197
- 保质期：
See instructions
- 英文名：
标签:Tag free
- 库存：
表达系统:E.coli
- 供应商：
上海经科化学科技有限公司
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥840.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥2520.0 |
| 规格： | 500ug | 产品价格： | ￥9840.0 |
| 规格： | 1mg | 产品价格： | ￥14080.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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文献和实验Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
Dopaminergic Neuronal Differentiation Protocol for Human Mesenchymal Stem Cells
from the adult human bone marrow (BM) can be easily isolated and expanded in culture while maintaining their immense plasticity. Here, we describe a protocol to generate DA-producing cells from adult human MSCs using a cocktail that includes sonic hedgehog (SHH
Directed Differentiation of Dopamine Neurons from Human Pluripotent Stem Cells
including Parkinson’s disease. Availability of large quantities of human mDA neurons would greatly enhance our ability to reveal pathological processes underlying mDA neuron degeneration and to identify treatments for these neurological conditions. Human
人垂体肿瘤（human pituitary tumors, HPA）起源于垂体前叶的内分泌细胞，约占所有颅内肿瘤的 15%，通常被认为是良性肿瘤。然而在手术治疗中发现，30-40% 病例发生了局部的侵袭性行为【1】。垂体瘤分为功能性垂体瘤和无功能性垂体瘤，根据瘤细胞分泌的激素将功能性垂体瘤再进一步分为：泌乳素细胞腺瘤（PRL），生长激素细胞腺瘤（GH），促肾上腺皮质激素细胞瘤（ACTH），促甲状腺素细胞瘤（TSH），促性腺激素细胞瘤（LH/FSH）及混合瘤和未分类腺瘤。 目前，侵袭性垂体
技术资料