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Human/Mouse/Rat TGFB3

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  • ¥1200 - 24400
  • SinoBio
  • 国产
  • CJ44
  • 2026年04月27日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:Ala301-Ser412(Tyr340Phe)

    • 保质期

      See instructions

    • 英文名

      标签:Tag free

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1200.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥15250.0
    规格:1mg产品价格:¥24400.0
    产品描述
    Recombinant Human/Mouse/Rat Transforming Growth Factor Beta 3 is produced by our Mammalian expression system and the target gene encoding Ala301-Ser412(Tyr340Phe) is expressed.
     
    蛋白编号
    P10600
     
    产品别称
    Transforming growth factor beta-3; TGFB3; TGF-beta-3; Latency-associated peptide; LAP
     
    分子量
    12.7 KDa
     
    表观分子量
    12-14 KDa, reducing conditions
     
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH 2.5.
     
    内毒素
    < 0.01 EU/µg as determined by LAL test.
     
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
     
    生物活性-Cell Based Assay
    Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells. The ED50 for this effect is 10-80 pg/ml. (QC verified)
     
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
     
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
     
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
     
    产品背景
    Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate.

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    图标文献和实验
    该产品被引用文献

    Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate.

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    文献支持
    Human/Mouse/Rat TGFB3
    ¥1200 - 24400