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- 文献和实验
- 技术资料
- 保存条件:
蛋白表达区间:Ala18-Pro202
- 保质期:
See instructions
- 英文名:
标签:Tag free
- 库存:
表达系统:E.coli
- 供应商:
上海经科化学科技有限公司
- 规格:
10ug/50ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥840.0 |
|---|---|---|---|
| 规格: | 50ug | 产品价格: | ¥2520.0 |
| 规格: | 500ug | 产品价格: | ¥12320.0 |
| 规格: | 1mg | 产品价格: | ¥17600.0 |
- Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
- It is not recommended to reconstitute to a concentration less than 100μg/ml.
- Dissolve the lyophilized protein in distilled water.
- Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- The product is shipped at ambient temperature.
- Upon receipt, store it immediately at the temperature listed below.
- Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
- Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
- Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
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文献和实验The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence homology. IL-17D is expressed preferentially in skeletal muscle, heart, adipose tissue, lung, pancreas, and nervous system. Like other IL-17 family members, IL-17D modulates immune responses indirectly by stimulating the production of myeloid growth factors and chemokines including IL-6, IL-8, and GM-CSF. IL-17D has also been shown to suppress the proliferation of myeloid progenitors in colony formation assays.
Immunity:「填补教科书」董晨院士团队解析 IL-17D 重要功能,并首次发现其受体
慢性炎症与自身免疫性疾病、过敏性疾病和肿瘤的发展密切相关,炎性因子白介素 - 17(IL-17)家族在促进宿主防御和自身免疫性疾病中起着重要作用。IL-17 家族由六个成员组成(包括 IL-17A、B、C、D、E、F),IL-17D 是 IL-17 家族中了解最少的成员,其受体也尚不明确。 图片来源:Frontiers in Immunology(1)2021 年 4 月 13 日,清华大学医学院董晨院士团队在 Immunity 上在线发表了题为 Interleukin-17D
Human IL-2 Enzyme Immunoassay (EIA)
Increased division and maturation of activated helper T cells Stimulation of neutrophils Stimulus for the secretion of interferon-( and tumor necrosis factors - aphla and - Beta from peripheral mononuclear cells. The Endogen Human IL-
Evaluation of IL-2-Withdrawal-Induced Apoptosis in Human T Lymphocytes
pathway of lymphocyte apoptosis triggered by starvation for IL-2 or other survival cytokines.
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