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Human HLA-A*0201 PRAME complex

Protein
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  • ¥840 - 17600
  • SinoBio
  • 国产
  • C32W
  • 2025年11月10日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      蛋白表达区间:(ALYVDSLFFL)&Ile21-Met119&Gly25-Ile308(Ala269Val)

    • 保质期

      See instructions

    • 英文名

      标签:C-10His

    • 库存

      表达系统:Human Cells

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥840.0
    规格:50ug产品价格:¥2520.0
    规格:500ug产品价格:¥12320.0
    规格:1mg产品价格:¥17600.0
    产品描述
    Recombinant Human Melanoma antigen preferentially expressed in tumors is produced by our Mammalian expression system and the target gene encoding (ALYVDSLFFL)&Ile21-Met119&Gly25-Ile308(Ala269Val) is expressed with a 10His tag at C terminus.
    蛋白编号
    P61769&
    A0A140T913
    产品别称
    Human HLA-A*0201 PRAME complex Protein
    分子量
    50.9 KDa
    表观分子量
    49-62 KDa
    剂型描述
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH7.4.
    内毒素
    < 1 EU/µg as determined by LAL test.
    纯度-SDS-PAGE
    Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
    复溶
    • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
    • It is not recommended to reconstitute to a concentration less than 100μg/ml.
    • Dissolve the lyophilized protein in distilled water.
    • Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    运输条件
    • The product is shipped at ambient temperature.
    • Upon receipt, store it immediately at the temperature listed below.
    保存条件
    • Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
    • Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
    • Aliquots of reconstituted samples are stable at ≤ -20°C for 1 months.
    产品背景
    Preferentially expressed antigen in melanoma (PRAME) is a cancer testis antigen (CTA) identified in 1997 through analysis of the specificity of tumor-reactive T-cell clones derived from a patient with metastatic cutaneous melanoma. PRAME expression was associated with the largest basal diameter (LBD) and tumor volume. Notwithstanding, PRAME expression can appear at any stage of tumor progression and not only in advanced stages. These findings were in agreement with the already known strong association of LBD with GEP and metastatic risk. Regarding its cellular functions, PRAME has been identified as a repressor of the retinoic acid receptor (RAR) signaling.

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    图标文献和实验
    该产品被引用文献

    Preferentially expressed antigen in melanoma (PRAME) is a cancer testis antigen (CTA) identified in 1997 through analysis of the specificity of tumor-reactive T-cell clones derived from a patient with metastatic cutaneous melanoma. PRAME expression was associated with the largest basal diameter (LBD) and tumor volume. Notwithstanding, PRAME expression can appear at any stage of tumor progression and not only in advanced stages. These findings were in agreement with the already known strong association of LBD with GEP and metastatic risk. Regarding its cellular functions, PRAME has been identified as a repressor of the retinoic acid receptor (RAR) signaling.

    相关实验
    • Quantitative Analysis of PRAME for Detection of Minimal Residual Disease in Leukemia

      Preferentially expressed antigen of melanoma (PRAME) was first isolated using cDNA expression cloning techniques as a gene encoding a human melanoma antigen recognized by melanoma reactive cytotoxic T-cells (CTL) (1 ). This gene codes

    • Purification of Human Complement Protein C5

      Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. Whereas purification of its paralogues C3 and C4 from plasma is relatively

    • Purification of the human TATA-Binding Protein, TBP

      The TATA-binding protein TBP plays a central role in eukaryotic transcription initiation (1 , 2 ). TBP binds to the promoter consensus sequence TATAAA, located approx 30 nucleotides upstream of the transcriptional start site. Once bound, TBP

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    文献支持
    Human HLA-A*0201 PRAME complex Protein
    ¥840 - 17600