大家都在搜
手机验证
发货周期:现货
博士德生物
cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Mouse
96T
货号 | EK1277 |
---|---|
产品名称 | Mouse DLL4 ELISA Kit |
产品描述 | For quantitative detection of mouse DLL4 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
免疫原 | NSO, S28-P525 |
交叉反应 | There is no detectable cross-reactivity with other relevant proteins. |
敏感性 | <10pg/ml |
检测范围 | 15.6pg/ml-1000pg/ml |
基因名称 | DLL4 |
基因全名 | delta-like 4 (Drosophila) |
Uniprot ID | Q9JI71 |
指标别名 | Delta 4 | Delta4 | Delta ligand 4 | Delta like 4 | DLL 4 | DLL4 | hdelta2 | Homeobox protein DLL-4 | Notch ligand delta 2 | Notch ligand DLL4 | XDLL-4 | Q9NR61 |
背景资料 | Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs), in particular to arteries and capillaries, and is involved in vascular development, and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. Mouse DLL4 could activate mouse Notch1 and mouse Notch4. DLL4 acts as a negative regulator of tumor angiogenesis, its blockade results in the striking uncoupling of tumor growth from vessel density, presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it, this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge. |
显色时间 | 25-30分钟 |
SKU | 名称 | 数量 |
Catalog number | Description | Quantity |
EK1277-CAP | 96-well plate precoated with anti- mouse DLL4 antibody | 1 |
EK1277-ST | Lyophilized recombinant mouse DLL4 standard | 10ng/tube×2 |
EK1277-DA | Biotinylated anti- mouse DLL4 antibody | 100μl(dilution 1:100) |
AR1103 | Avidin-Biotin-Peroxidase Complex (ABC) | 100μl(dilution 1:100) |
AR1106-1 | Sample diluent buffer | 30ml |
AR1106-2 | Antibody diluent buffer | 12ml |
AR1106-3 | ABC diluent buffer | 12ml |
AR1104 | TMB color developing agent | 10ml |
AR1105 | TMB stop solution | 10ml |
PLA-SEA | Adhesive cover | 4 |
Intra-Assay Precision | Inter-Assay Precision | |||||
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 16 | 16 | 16 | 24 | 24 | 24 |
Mean(pg/ml) | 40 | 244 | 515 | 40 | 242 | 520 |
Standard deviation | 2.44 | 18.78 | 36.56 | 2.64 | 20.81 | 38.48 |
CV(%) | 6.1% | 7.7% | 7.1% | 6.6% | 8.6% | 7.4% |
Concentration(pg/ml) | 0 | 15.6 | 31.2 | 62.5 | 125 | 250 | 500 | 1000 |
O.D. | 0.067 | 0.105 | 0.177 | 0.313 | 0.569 | 1.059 | 1.781 | 2.295 |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。