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KX2-391S2700

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  • ¥737
  • selleckchem
  • 进口
  • S2700
  • 2025年07月08日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      低温

    • 库存

      大量

    • 供应商

      上海善然生物科技有限公司

    • 规格

      5mg

    KX2-391 is a Src inhibitor that is directed to the Src substrate pocket. KX2-391 shows steep dose-response curves against Huh7 (GI 50 = 9 nM), PLC/PRF/5 (GI 50 = 13 nM), Hep3B (GI 50 = 26 nM), and HepG2 (GI 50 = 60 nM), four hepatic cell cancer (HCC) cell lines. [1] KX2-391 is found to inhibit certain leukemia cells that are resistant to current commercially available drugs, such as those derived from chronic leukemia cells with the T3151 mutation. KX2-391 is evaluated in engineered Src driven cell growth assays inNIH3T3/c-Src527F and SYF/c-Src527F cells and exhibits GI50 with 23 nM and 39 nM, respectively. [2]

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    相关实验
    • RNA Silencing and Antiviral Defense in Plants

      391:806–811, 1998; Waterhouse et al., Proc Natl Acad Sci U S A 95:13959–13964, 1998), intense research efforts have resulted in much progress from the speculation of Mello and colleagues that “the mechanisms underlying RNA interference probably exist

    • 关于为什么烷基化后PMF检索要选carbamidomethyl(C)

      0003-2700(01)00342-0 Not subject to U.S. Copyright. Published 2001 American Chemical Society Overalkylation of a Protein Digest with Iodoacetamide Emily S. Boja and Henry M. Fales* National Heart, Lung and Blood Institute, National Institutes

    • 如何分析DNA测序结果

      Weak G's after A's   A common base miscall is a G that follows an A. The rate of incorporation of G's after A's by the enzyme is low. Compare the signal intensity of the G at base 372 and 375 with the G at base 391

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