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文献和实验Screening for Candidate Mutations Causing von Willebrands Disease (vWD)
von Willebrand factor (vWF) is a large, complex glycoprotein that exists in plasma and platelets, and is synthesized by megakaryocytes and endothelial cells. vWF plays an essential role in hemostasis in at least two ways. It is involved
Protein Body Induction: A New Tool to Produce and Recover Recombinant Proteins in Plants
inside PBs. Zera domain fused to several proteins, including a enhanced cyan fluorescent protein (ECFP), calcitonin (Ct) and epidermal growth factor (EGF), were cloned into vectors for transient or stable transformation of tobacco plants. In tobacco leaves
Snake Venom Toxins Affecting Platelet Function
sequence and crystal structure have been determined, and specific binding sites within the A1 domain of von Willebrand factor have been identified (2 –8 ). Interestingly, members of the metalloproteinase-disintegrin family of snake venom proteins—
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