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Sigma-Aldrich货号D2438二甲基亚砜DMSO上

海睿安生物19121878899默克Merck-Millipore-Roche-Sigma官方正式授权代理商
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  • ¥2288.32
  • Sigma-Aldrich
  • made in USA
  • D2438
  • 2026年01月17日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 英文名

      DMSO

    • CAS号

      67-68-5

    • 保质期

      1年

    • 保存条件

      Room Temperature

    • 库存

      30⁺瓶

    • 供应商

      上海睿安生物19121878899

    • 规格

      5╳10ml

    Sigma-Aldrich货号D2438二甲基亚砜DMSO上海睿安生物19121878899默克Merck-Millipore-Roche-Sigma官方正式授权代理商

    二甲基亚砜

    sterile-filtered,BioPerformance Certified,meets EP,USP testing specifications,suitable for hybridoma

    别名:DMSO,甲基亚砜

    属性

    产品名称:二甲基亚砜,sterile-filtered,BioPerformance Certified,meets EP,USP testing specifications,suitable for hybridoma

    InChI key:IAZDPXIOMUYVGZ-UHFFFAOYSA-N

    InChI:1S/C2H6OS/c1-4(2)3/h1-2H3

    SMILES string:CS(C)=O

    grade:BioPerformance Certified

    产品细节图片1

    说明

    Application:二甲基亚砜已被用在体内培养和诱导肝星状细胞(HSC)活化中的载体对照。它还被用于制备储备溶液,以研究阿魏酸(FA)对髓核(NP)细胞的细胞毒性。

    Disclaimer:在室温下容易过冷并缓慢重融。固化产品可以通过加热至室温来重新液化,而不会损害产品。

    Features and Benefits:即用型无菌过滤产品,被方便地包装在隔垫螺帽琥珀色瓶中。符合USP和EP检测的要求

    General description

    二甲基亚砜(DMSO)是一种非质子溶剂。不溶于水的治疗性和有毒分子通常溶于DMSO。液氮与诸如DMSO的冷冻保护剂结合使用是广泛使用的细胞保存方法。DMSO已用于制备多种分子的储备溶液,并同时也作为这些分子的对照。它已用于溶解迁移后细胞的细胞迁移试验。经BPC测试的DMSO也可满足生物技术和组织工程应用的要求。
    产品细节图片2

    常见问题

    1. What is the molarity of DMSO?

      DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

    2. What is the DMSO dissolved in?

      DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

    3. Where does DMSO come from?

      DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

    4. What concentration of DMSO do I use in a cell freezing media?

      DMSO is usually used at 1-10%, depending on the cell line. For the cell freezing media that we offer, it is used at 8.7% concentration.

    5. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    6. What is the specification for 'pass' for cell freezing on the Certificate of Analysis for Dimethyl sulfoxide (DMSO)?

      Product D2438 is assessed for cell freezing. Cells are frozen and stored at -70°C. The cells are thawed, cultured and viability is assessed at 24 hours. There is no evidence of cytotoxicity or abnormal cell growth.

    7. Dimethyl sulfoxide (DMSO) should be a liquid. Why did it arrive as a solid?

      DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

    8. What is the basis for the endotoxin specification for Dimethyl sulfoxide (DMSO)?

      The industry standard for 'endotoxin free' is less than 1 EU/mL.

    What is the difference between Dimethyl sulfoxide (DMSO) Products. D1435 and D2438?

    Products D1435 and D2438 both meet the USP specifications. The D2438 is sterile-filtered, but D1435 is not. Furthermore, the D2438 is quality control tested for endotoxin and use-tested for cell freezing.

    What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

    How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.

    What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

    My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

    同行评审论文(部分:文献)

    Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR.
    A Oguro-Ando et al.
    Molecular psychiatry, 20(9), 1069-1078 (2014-10-15)
    Rare maternally inherited duplications at 15q11-13 are observed in ~1% of individuals with an autism spectrum disorder (ASD), making it among the most common causes of ASD. 15q11-13 comprises a complex region, and as this copy number variation encompasses many
    How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.
    Caroline Godfrey et al.
    Human molecular genetics, 24(15), 4225-4237 (2015-05-03)
    Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of dystrophin protein. Despite this, the relationship between restoring dystrophin to established dystrophic muscle and its ability to induce clinically relevant changes in muscle
    Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
    Claudia C Faria et al.
    Cancer research, 75(1), 134-146 (2014-11-14)
    Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from the matched primary tumor. Effective and less toxic therapies
    High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays.
    Mike Clements et al.
    Toxicological sciences : an official journal of the Society of Toxicology, 140(2), 445-461 (2014-05-09)
    Human stem cell derived cardiomyocytes (hESC-CM) provide a potential model for development of improved assays for pre-clinical predictive drug safety screening. We have used multi-electrode array (MEA) analysis of hESC-CM to generate multi-parameter data to profile drug impact on cardiomyocyte
    Identification and characterisation of small molecule inhibitors of feline coronavirus replication.
    Phillip McDonagh et al.
    Veterinary microbiology, 174(3-4), 438-447 (2014-12-04)
    Feline infectious peritonitis (FIP), a feline coronavirus (FCoV) induced disease, is almost invariably fatal with median life expectancy measured in days. Current treatment options are, at best, palliative. The objectives of this study were to evaluate a panel of nineteen

    产品细节图片3

    产品细节图片4产品细节图片5产品细节图片6产品细节图片7产品细节图片8产品细节图片9

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    图标文献和实验
    该产品被引用文献

    Sigma-Aldrich货号D2438二甲基亚砜DMSO上海睿安生物19121878899默克Merck-Millipore-Roche-Sigma官方正式授权代理商

    二甲基亚砜

    sterile-filtered,BioPerformance Certified,meets EP,USP testing specifications,suitable for hybridoma

    别名:DMSO,甲基亚砜

    属性

    产品名称:二甲基亚砜,sterile-filtered,BioPerformance Certified,meets EP,USP testing specifications,suitable for hybridoma

    InChI key:IAZDPXIOMUYVGZ-UHFFFAOYSA-N

    InChI:1S/C2H6OS/c1-4(2)3/h1-2H3

    SMILES string:CS(C)=O

    grade:BioPerformance Certified

    引用文献图片1

    说明

    Application:二甲基亚砜已被用在体内培养和诱导肝星状细胞(HSC)活化中的载体对照。它还被用于制备储备溶液,以研究阿魏酸(FA)对髓核(NP)细胞的细胞毒性。

    Disclaimer:在室温下容易过冷并缓慢重融。固化产品可以通过加热至室温来重新液化,而不会损害产品。

    Features and Benefits:即用型无菌过滤产品,被方便地包装在隔垫螺帽琥珀色瓶中。符合USP和EP检测的要求

    General description

    二甲基亚砜(DMSO)是一种非质子溶剂。不溶于水的治疗性和有毒分子通常溶于DMSO。液氮与诸如DMSO的冷冻保护剂结合使用是广泛使用的细胞保存方法。DMSO已用于制备多种分子的储备溶液,并同时也作为这些分子的对照。它已用于溶解迁移后细胞的细胞迁移试验。经BPC测试的DMSO也可满足生物技术和组织工程应用的要求。
    引用文献图片2

    常见问题

    1. What is the molarity of DMSO?

      DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

    2. What is the DMSO dissolved in?

      DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

    3. Where does DMSO come from?

      DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

    4. What concentration of DMSO do I use in a cell freezing media?

      DMSO is usually used at 1-10%, depending on the cell line. For the cell freezing media that we offer, it is used at 8.7% concentration.

    5. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    6. What is the specification for 'pass' for cell freezing on the Certificate of Analysis for Dimethyl sulfoxide (DMSO)?

      Product D2438 is assessed for cell freezing. Cells are frozen and stored at -70°C. The cells are thawed, cultured and viability is assessed at 24 hours. There is no evidence of cytotoxicity or abnormal cell growth.

    7. Dimethyl sulfoxide (DMSO) should be a liquid. Why did it arrive as a solid?

      DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

    8. What is the basis for the endotoxin specification for Dimethyl sulfoxide (DMSO)?

      The industry standard for 'endotoxin free' is less than 1 EU/mL.

    What is the difference between Dimethyl sulfoxide (DMSO) Products. D1435 and D2438?

    Products D1435 and D2438 both meet the USP specifications. The D2438 is sterile-filtered, but D1435 is not. Furthermore, the D2438 is quality control tested for endotoxin and use-tested for cell freezing.

    What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

    How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.

    What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

    My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

    同行评审论文(部分:文献)

    Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR.
    A Oguro-Ando et al.
    Molecular psychiatry, 20(9), 1069-1078 (2014-10-15)
    Rare maternally inherited duplications at 15q11-13 are observed in ~1% of individuals with an autism spectrum disorder (ASD), making it among the most common causes of ASD. 15q11-13 comprises a complex region, and as this copy number variation encompasses many
    How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.
    Caroline Godfrey et al.
    Human molecular genetics, 24(15), 4225-4237 (2015-05-03)
    Splice modulation therapy has shown great clinical promise in Duchenne muscular dystrophy, resulting in the production of dystrophin protein. Despite this, the relationship between restoring dystrophin to established dystrophic muscle and its ability to induce clinically relevant changes in muscle
    Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
    Claudia C Faria et al.
    Cancer research, 75(1), 134-146 (2014-11-14)
    Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from the matched primary tumor. Effective and less toxic therapies
    High-throughput multi-parameter profiling of electrophysiological drug effects in human embryonic stem cell derived cardiomyocytes using multi-electrode arrays.
    Mike Clements et al.
    Toxicological sciences : an official journal of the Society of Toxicology, 140(2), 445-461 (2014-05-09)
    Human stem cell derived cardiomyocytes (hESC-CM) provide a potential model for development of improved assays for pre-clinical predictive drug safety screening. We have used multi-electrode array (MEA) analysis of hESC-CM to generate multi-parameter data to profile drug impact on cardiomyocyte
    Identification and characterisation of small molecule inhibitors of feline coronavirus replication.
    Phillip McDonagh et al.
    Veterinary microbiology, 174(3-4), 438-447 (2014-12-04)
    Feline infectious peritonitis (FIP), a feline coronavirus (FCoV) induced disease, is almost invariably fatal with median life expectancy measured in days. Current treatment options are, at best, palliative. The objectives of this study were to evaluate a panel of nineteen

    引用文献图片3

    引用文献图片4引用文献图片5引用文献图片6引用文献图片7引用文献图片8引用文献图片9

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    Sigma-Aldrich货号D2438二甲基亚砜DMSO上海睿安生物19121878899默克Merck-Millipore-Roche-Sigma官方正式授权代理商
    ¥2288.32