AMINO ACIDS, BRANCHED CHAIN ST

分支氨基酸 branched chain amino acid

亦称为侧链氨基酸。在自然氨基酸中，指缬氨酸、白氨酸、异白氨酸之综合名称。这些氨基酸β位γ位有甲基，结构相似，代谢上也具有同样的或共同的途径，可被具共同底物特异性的酶所催化。另外由于这种原因，三者之间进行营养学的相互颉颃。由分支氨基酸代谢的先天性酶缺乏所引起的病症，称为槭糖尿病。  

Synthesis of Side Chain N,N' -Diaminoalkylated Derivatives of Basic Amino Acids for Application in Solid-Phase Peptide Synthesis

to improve their pharmacological properties. Inspired by the importance of basic amino acids in biological systems and the remarkable versatility displayed by lysine during the synthesis of complex peptide scaffolds, this chapter describes a simple procedure

Cyclic Aromatic Amino Acids with Constrained 1 and 2 Dihedral Angles

, the term “topographic design on a stable template” was proposed ( 3 ). The side chain χ 1 of aromatic amino acids, such as Phe, Trp, Tyr, and His, can be constrained in either the gauche (−) or gauche (+) conformation by linking the nitrogen atom