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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
Chemokine (C-C Motif) Receptor 7 (CCR7) 抗体
- 规格:
0.1ml/0.2ml
Chemokine (C-C Motif) Receptor 7 (CCR7) 抗体
anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibody
抗原
Chemokine (C-C Motif) Receptor 7 (CCR7)
别名 zgc:165629, ccr7-a, CD197, Cdw197, Cmkbr7, EBI1, Ebi1h, BLR2, CDw197, CMKBR7
适用
其他选择 小鼠
宿主
其他选择 大鼠
克隆类型 (克隆位点)
单克隆 (4B12)
标记
其他选择 非结合性
应用范围
其他选择 流式细胞分析技术(FACS), 免疫沉淀(IP)
Pubmed 找到1个引用
规格 0.1 mg
发货至 中国 (更改)
发货时间 29至35个工作日
产品细节 Chemokine (C-C Motif) Receptor 7 (CCR7) 抗体
免疫原 CCR7 rat basophilic leukaemia (RBL)-2H3 transfectants. Spleen cells from immunised Lou/c rats were fused with cells of the mouse X63.Ag8.653 myeloma cell line.
克隆位点 4B12
亚型 IgG2a
特异性 This antibody recognises CD197. Clone 4B12 does not block the binding of the ligand to CD197.
纯化方法 Affinity chromatography on Protein G
目标详细情况Chemokine (C-C Motif) Receptor 7 (CCR7) 抗体
别名 CD197 / CCR7
背景 CD197 is a 43kD member of the G-protein coupled receptor family, which is commonly known as chemokine receptor 7 (CCR7). In mice, CD197 is expressed on most naive T cells, a subset of memory T cells, B cells, mature dendritic cells, NK cells, a subset of thymocytes and CD34+ macrophage progenitor cells. CD197 is a functional receptor for chemokines CCL21 and CCL19. The receptor plays an important role in regulating the trafficking and homing of lymphocytes and dendritic cells to secondary lymphoid organs.Synonyms: BLR2, C-C CKR-7, C-C chemokine receptor type 7, CC-CKR-7, CCR-7, CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1, EVI1, MIP-3 beta receptor
基因ID 10090
UniProt P47774
研究领域 CD Antigens, Surface Receptors of Immune Cells
使用细节 Chemokine (C-C Motif) Receptor 7 (CCR7) 抗体
应用备注 Flow cytometry: 1/25 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Chemokine (C-C Motif) Receptor 7 (CCR7) 抗体
浓度 1.0 mg/mL IgG
缓冲液 PBS, pH 7.4 containing 0.09 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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文献和实验Characterization of Chemokine Receptors
., DiGregorio, D., Mak, J.Y., Horuk, R., and Schall, T.J. 1993. Molecular cloning, functional expression, and signaling characteristics of a C‐C chemokine receptor. Cell. 72:415‐425.
C value|C值[单倍基因组DNA的量] C value paradox|C值悖理[物种的C值和它的进化复杂性之间无严格对应关系] C4 dicarboxylic acid cycle|C4二羧酸循环 cachectin|恶液质素[即alfa肿瘤坏死因子] cadaverine|尸胺 cadherin|钙粘着蛋白[介导依赖(于)钙的细胞间粘着作用的一类跨膜蛋白质,分为E-,N-,P-等若干
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 大鼠趋化因子受体 7(CCR7)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和尿液生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗大鼠 CCR7 单抗包被于酶标板上,标准品和样品中的 CCR7 与单抗结合,加入生物素化的抗大鼠 CCR7 ,形成免疫复合物连接在板上
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