Superoxide Dismutase 1, Solubl

Superoxide Dismutase 1, Soluble (SOD1) 抗体抗原
Superoxide Dismutase 1, Soluble (SOD1)
别名
sod1, SODC, DKFZP469M1833, LOC692639, ALS, Albs, mKIAA4111, Als, CG11793, Cu, Cu-Zn SOD, Cu/Zn SOD, Cu/Zn sod, Cu/Zn superoxide dismutase, Cu/ZnSOD, CuSOD, CuZn SOD, CuZn-SOD, CuZn-SOD1, CuZnSOD, Cu[2 ... show more
适用
其他选择 牛, 人, 小鼠, 大鼠
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Immunohistochemistry (Frozen Sections) (IHC (fro)), 酵素免疫分析法（EIA）, 免疫沉淀（IP）, Western Blotting (WB)
Pubmed 6个引用可参考
规格 25 μg
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb264855
产品细节 Superoxide Dismutase 1, Soluble (SOD1) 抗体
免疫原 Rat Cu/Zn SOD
亚型 IgG
特异性 Detects a 23 kDa (Human) and 19 kDa (other species) proteins corresponding to the Molecular Mass of Cu/Zn Superoxide Dismutase (SOD) on SDS-PAGE Immunoblots.
纯化方法 Antigen Affinity Chromatography
目标详细情况 Superoxide Dismutase 1, Soluble (SOD1) 抗体
别名 Superoxide Dismutase 1 / SOD1
背景 Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (Ref.3). It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (Ref.2,5). In general, SODs play a major role in antioxidant defense mechanisms. (Ref.4) There are two main types of SOD in mammalian cells. One form (SOD1) contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cysteines forming an intra-subunit disulphide bridge (Ref.3). The second form (SOD2) is a manganese containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form (SOD3 or EC-SOD) is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDA and it exists only in the extra-cellular space (Ref.7). SOD3 can also be distinguished by its heparinbinding capacity (Ref.1).Synonyms: ALS1, CuZn-SOD, CuZnSOD, IPOA, SOD-1, Superoxide dismutase [Cu-Zn]
基因ID 6647
NCBI登录号 NP_000445
UniProt P00441
研究领域 Inflammation, Enzymes, Metabolism
使用细节 Superoxide Dismutase 1, Soluble (SOD1) 抗体
应用备注 Western blot: 0.5 μg/mL was sufficient for detection of Cu/Zn SOD in 20 μg of rat braintissue extract by Colorimetric Immunoblot analysis using Goat anti-RabbitIgG-AP as the secondary antibody. (Ref.6)Immunoprecipitation. EIA (Ref.6). Immunohistochemistry on Frozen Sections (Ref.8).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Superoxide Dismutase 1, Soluble (SOD1) 抗体
状态 Liquid
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.0, 0.09 % Sodium Azide, 50 % Glycerol
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.