Integrin alpha 2 (ITGA2) 抗体 (P

Integrin alpha 2 (ITGA2) 抗体 (PE)抗原
Integrin alpha 2 (ITGA2)
别名 PGI, gpi, pgi-1, wu:fc02c05, zgc:86919, CD49B, DX5, BR, GPIa, HPA-5, VLA-2, VLAA2
适用
其他选择 人, 猴
宿主
其他选择 小鼠
克隆类型 (克隆位点)
单克隆 (AK7)
标记
其他选择 PE
应用范围
其他选择 流式细胞分析技术（FACS）
Pubmed 5个引用可参考
规格 100 tests
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb118701
产品细节 Integrin alpha 2 (ITGA2) 抗体 (PE)
克隆位点 AK7
亚型 IgG1
特异性 Recognizes the Integrin alpha 2 subunit (CD49b), which is a 160 kDa glycoprotein that non-covalently associates with the 130 kDa integrin beta1 subunit to form the VLA-2 complex.
纯化方法 Affinity Chromatography on Protein G
目标详细情况Integrin alpha 2 (ITGA2) 抗体 (PE)
别名 CD49b / ITGA2
背景 Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50 % of monocytes and most adherent cell lines.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
基因ID 3673
NCBI登录号 NP_002194
UniProt P17301
研究领域 CD Antigens, Surface Receptors of Immune Cells, Cell/Tissue Markers, Extracellular Matrix, Signaling
使用细节 Integrin alpha 2 (ITGA2) 抗体 (PE)
应用备注 Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells or 100 μL human whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Integrin alpha 2 (ITGA2) 抗体 (PE)
溶解方式 Restore with 1.0 mL distilled water.
缓冲液 PBS, pH 7.2 with 0.09 % Sodium Azide as preservative, 1 % BSA and 5 % Sucrose.
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!