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- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
Cathepsin F (CTSF) (Middle Region) 抗体
- 规格：
0.1ml/0.2ml
Cathepsin F (CTSF)
别名 CTSF, MGC140519, cb420, sb:cb420, zgc:153093, LOC100101596, Ctsf, ACYPI000376, catf, CATSF, CLN13, AI481912
抗原表位
其他选择 Middle Region
适用
其他选择 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 酵素免疫分析法（EIA）, Western Blotting (WB)
Pubmed 2个引用可参考
规格 0.4 mL
发货至 中国 (更改)
发货时间 29至35个工作日
产品编号 yb452888
产品细节 Cathepsin F (CTSF) (Middle Region) 抗体
免疫原 KLH conjugated synthetic peptide selected from the Center region of human CTSF
特异性 This antibody detects Cathepsin F at Center, D276.
交叉反应 （详细） Species reactivity (tested):Human
纯化方法 Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
目标详细情况 Cathepsin F (CTSF) (Middle Region) 抗体
别名 Cathepsin F
背景 Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF is a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway.Synonyms: CATSF, CTSF
分子量 53366 Da
基因ID 8722
NCBI登录号 NP_003784
UniProt Q9UBX1
研究领域 Immunology, Innate Immunity, Proteases
使用细节 Cathepsin F (CTSF) (Middle Region) 抗体
应用备注 Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
贮存及处理 Cathepsin F (CTSF) (Middle Region) 抗体
状态 Liquid
浓度 0.25 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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文献和实验。一个抗体分子上的两个抗原结合部位是相同的，位于两臂末端称抗原结合片段（antigen-binding fragment，Fab）。糖结合在结晶片段（crystalline fragment，FC）上。 基本结构 重链（heavy chain，H）2条 轻链（light chain，L）2条 可变区（variable region，V区）
F factor|F因子 Fab fragment|Fab片段[免疫球蛋白上结合抗原的片段] fabavirus|蚕豆病毒组[一组植物病毒，模式成员是蚕豆萎蔫病毒] face centered lattice|面心点格 face mask|面具 face protector|面具 face shield|面罩 facilitated
within an internal region of PEDF (pigment endothelium-derived factor) of human origin. S P E C I F I C I T Y PEDF (I -15) is recommended for detection of precursor and matu re PEDF of mou se, ra t an d human origin by Western blotting, immunoprecipitation
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