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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20℃
- 克隆性:
单克隆
- 抗体名:
HIV-1 Tat Specific Factor 1 (HTATSF1) (C-Term) 抗体
- 规格:
0.1ml/0.2ml
HIV-1 Tat Specific Factor 1 (HTATSF1)
别名 zgc:66252, MGC98898, HTATSF1, DKFZp468B086, 1600023H17Rik, 2600017A12Rik, 2700077B20Rik, TAT-SF1, TATSF1, dJ196E23.2, RGD1563377
抗原表位
其他选择 C-Term
适用
其他选择 小鼠, 大鼠, 犬, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 Western Blotting (WB)
Pubmed 找到1个引用
规格 50 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb182432
产品细节HIV-1 Tat Specific Factor 1 (HTATSF1) (C-Term) 抗体
免疫原 Synthetic peptide directed towards the C terminal of human HTATSF1
序列 EKVLDEEGSE REFDEDSDEK EEEEDTYEKV FDDESDEKED EEYADEKGLE
预测反应 Human : 100 %, Mouse : 90 %, Rabbit : 90 %, Rat : 90 %, Bovine : 80 %, Guinea pig : 80 %, Dog : 70 %
产品特性 This is a rabbit polyclonal antibody against HTATSF1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
目标详细情况 HIV-1 Tat Specific Factor 1 (HTATSF1) (C-Term) 抗体
别名 HTATSF1
背景 Whereas most DNA sequence-specific transcription factors increase the rate of initiation and interact with enhancer or promoter DNA, human immunodeficiency virus-1 (HIV-1) Tat predominantly stimulates elongation and interacts with the trans-acting responsive (TAR) RNA element. Tat is essential for HIV replication.
分子量 86 kDa
基因ID 27336
NCBI登录号 NM_014500, NP_055315
UniProt O43719
使用细节HIV-1 Tat Specific Factor 1 (HTATSF1) (C-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 755 AA
限制 仅限研究用
贮存及处理 HIV-1 Tat Specific Factor 1 (HTATSF1) (C-Term) 抗体
状态 Lyophilized
溶解方式 Add 50 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C
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文献和实验HIV-1 Chromatin, Transcription, and the Regulatory Protein Tat
in the viral promoter region in response to different cellular stimuli or drug treatments represents an important aspect of our understanding of HIV-1 transcription. Moreover, the viral transactivator Tat protein potently activates HIV-1 transcription
【进展|热点】PD-1信号通过上调BATF抑制HIV特异性CD8阳性T细胞的功能
Nat Med. 2010 Oct;16(10):1147-51. Epub 2010 Oct 3. Transcriptional analysis of HIV-specific CD8(+) T cells shows that PD-1 inhibits T cell function by upregulating BATF. Quigley M, Pereyra F, Nilsson B, et al. Department of Pediatric Oncology
system that originates from membrane shuttling proteins such as the Drosophila homeobox protein Antennapedia, the HIV-1 transcriptional factor TAT and VP22 from HSV-1 has advantages for targeted delivery compared with standard translocation techniques. This transport
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