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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 英文名：
THP1; THP 1; THPI; THP-1(ATCC); THP-1-O; O-THP-1; Tohoku Hospital Pediatrics-1
- 库存：
复苏：1-2周。冻存：现货。（建议:复苏为主，极个别特殊情况选冻存）
- 供应商：
上海富衡生物科技有限公司
- 肿瘤类型：
急性单核细胞白血病
- 细胞类型：
真核细胞
- 品系：
人源单核细胞白血病细胞系
- 组织来源：
外周血组织
- 相关疾病：
急性单核细胞白血病
- 物种来源：
人源
- 免疫类型：
免疫细胞系（髓系，天然免疫相关）
- 细胞形态：
单核细胞
- 是否是肿瘤细胞：
是
- 器官来源：
骨髓
- 运输方式：
常温/干冰，快递运输
- 年限：
数年
- 生长状态：
悬浮生长
- 规格：
1 × 10⁶ cells/T25 flask/冻存管
| 规格： | 1 × 10⁶ cells/T25 flask | 产品价格： | ￥1400.0 |
|---|---|---|---|
| 规格： | 冻存管 | 产品价格： | ￥1700.0 |
THP-1 细胞系源自一名 1 岁墨西哥裔男性急性单核细胞白血病（AML-M5 型）患者的外周血，该患者处于疾病复发阶段。急性单核细胞白血病属于髓系白血病的一种，其特征是骨髓和外周血中单核细胞异常增殖，患者常表现为贫血、感染及出血倾向。
| 产品名称 | 人单核细胞白血病细胞；THP-1(STR) |
|---|---|
| 品牌 | FuHeng |
| 英文名 | THP-1 |
| 货号 | FH0112 |
| 规格 | 1 × 10⁶ cells/T25 flask |
| 培养 | RPMI 1640 + 10% FBS + 1% P/S + 0.05 mM β- 巯基乙醇 |
| 别称 | THP1; THP 1; THPI; THP-1(ATCC); THP-1-O; O-THP-1; Tohoku Hospital Pediatrics-1 |
| 形态特征 | 单核细胞 |
| 生长特性 | 悬浮生长 |
| 培养基 | THP-1专用培养基 |
| 培养条件 | 气相：95% 空气，5% CO₂；温度：37 ℃ |
| 传代方法 | 维持细胞浓度在2~4×105~8×105/ml，勿超过1×106/ml；2~3天换液1次。 |
| 组织来源 | 外周血组织 |
| 产品分类 | 人源细胞系 |
| 特别声明 | 富衡细胞库承诺尽最大努力对实验细胞资源相关信息进行及时更新。但限于当时的技术条件，细胞库资料不保证其准确性。 |
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- 作者
- 内容
- 询问日期
文献和实验该产品被引用文献
| 论文标题 | DOI | 发表时间 | 期刊 | 影响因子 | 作者列表 |
| Lycorine inhibits the proliferation of acute myeloid leukemia cells by upregulating the expression of THBS1 | 10.1007/s00277-026-06777-9 | 2026-01-17 | ANNALS OF HEMATOLOGY | 2.4 | Wu Lunbi, Liu Peng, Jiang Bowen, Zhang Xiaodong, Zhao Enliang, Zhao Jingying, Zhu Fangxu, Xu Hongxin, Shi Kuo, Jian Baiyu |
| Saccharomyces/pearl ferment lysate filtrate repairs UVB-induced skin barrier damage by regulating Nrf2/HO-1 and JNK/MAPK signaling pathways | 10.1016/j.jphotobiol.2026.113366 | 2026-01-12 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 3.7 | Tanglin Liu, Biao Guo, Liying Tong, Hao Li, Caibing Wang, Kai Zang, Ruili Zhao, Xinyi Zhao, Chenglong Ye, Xiyun Ye, Yongyan Dang |
| SENP6 Restrains NLRP3 Inflammasome Activation via DeSUMOylation-Driven K48-Linked Ubiquitination of NLRP3 in Acute Lung Injury | 10.34133/research.1069 | 2026-01-12 | Research | 10.7 | Angran Gu, Bailun Wang, Yi Zhang, Chang Sun, Yi Wei, Jie Yan, Yizheng Yang, Yichen Wang, Runmeng Liu, Ruirui Zhang, Jifa Liu, Changping Gu, Yuelan Wang |
| Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections | 10.1042/CS20256616 | 2025-12-23 | CLINICAL SCIENCE | 7.7 | Liu Ziyu, Ren Ping, Xue Ying, Liu Shouyue, Li Shanyu, Li Yanan, Zhang Ying |
| Carpaine alleviates NASH-related fibrosis by targeting Nid1 to inhibit IL-6/JAK/STAT3 signaling and macrophage M1 polarization | 10.1016/j.ijbiomac.2025.149451 | 2025-12-03 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 8.5 | Fulin Nian, Yueying Chen, Jia Chen, Qiuyu Jiang, Fansheng Meng, Zhixue Chen, Xiaolan Lu, Xizhong Shen, Yuqin Li |
| Prognostic Value of BTG1 for Predicting Decitabine Sensitivity in De Novo Acute Myeloid Leukemia | 10.1016/j.isci.2025.114327 | 2025-12-02 | iScience | 4.1 | Shiyuan Zhang, Mengyuan Li, Bin Xu, Xiaojian Zhu, Xia Mao, Hao Zhou, Xiwen Tong, Shuai Su, Yi Zhu, Donghua Zhang |
| Targeting the CCL2-CCR2 axis with ursodeoxycholic acid attenuates monocyte migration and platelet clearance in immune thrombocytopenia | 10.1016/j.ejphar.2025.178412 | 2025-11-27 | EUROPEAN JOURNAL OF PHARMACOLOGY | 4.7 | Jiahui Han, Ruizhen Li, Huhemuren Bao, Yingchun Xi, Hui Liang, Siqin Bateer, Qingchun Wang |
| Ferroptosis-related oxidative stress activation in the acute phase of Kawasaki disease | 10.3389/fimmu.2025.1704978 | 2025-11-13 | Frontiers in Immunology | 5.9 | Xing Xue, Guangan Dai, Yixiang Lin, Lan He, Wei Sheng, Jingwei Sun, Fang Liu |
| Ketogenic diet inhibits glioma progression by promoting gut microbiota-derived butyrate production | 10.1016/j.ccell.2025.09.002 | 2025-09-25 | CANCER CELL | 44.5 | Ming-Liang Chen, Ying He, Xun-Hu Dong, Hao-Fei Liu, Ze-Xuan Yan, Xiao-Lu Lu, Qing-Qing Miao, Qing-Ning Zhao, Hang Zhang, Li Luo, Shuai Wang, Jing-Yuan Li, Dong-Fang Xiang, Yong Lin, Tian-Ran Li, Xin-Yue Zhou, Yang-Yang Zhou, Min Mao, Xia Zhang, Hong Wei, Yu Shi, Xin-Dong Liu, Yi-Fang Ping, Xiu-Wu Bian |
| Human papillomavirus-related syntaxin 11 reprograms tumor-associated macrophages to induce breast cancer cell apoptosis via PI3K/AKT signaling | 10.1186/s10020-025-01325-z | 2025-09-02 | MOLECULAR MEDICINE | 6.4 | Hu Chuan, Hu Tingting, Wen Jian, Jia Zengrong |
| Cinobufagin Inhibits Invasion and Migration of Non-Small Cell Lung Cancer via Regulating Glucose Metabolism Reprogramming in Tumor-Associated Macrophages | 10.2147/DDDT.S531190 | 2025-08-01 | Drug Design Development and Therapy | 5.1 | Ying Sun, Huitong Yang, Xue Mei, Jinchan Xia, Long Feng, Jianfeng Gao, Wei Jiang, Min Jiang, Xu Hao, Yilin Feng, Yunfeng Lian |
| An Anisotropic Gold-Palladium Heterostructured Nanosystem for Synergistically Overcoming Radioresistance and Enhancing Melanoma Radioimmunotherapy | 10.1002/advs.202500492 | 2025-06-17 | Advanced Science | 14.1 | Cheng Chen, Yuqi Huang, Wandong Wang, Minghao Chao, Weiguo Sun, Yinghui Kong, Guan Jiang, Yong Gao, Fenglei Gao |
| Plac1+ Tumor Cell-Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer | 10.1002/advs.202417312 | 2025-03-08 | Advanced Science | 14.1 | Xiaoyan Meng, Zhonglong Liu, Lu Zhao, Ran Li, Luoman Gan, Liren Cao, Jingjing Sun, Lingfang Zhang, Yue He |
| Macrophage-to-Myofibroblast Transition Contributes to Cutaneous Scarring Formation Through the TGF-β/Smad3 Signaling Pathways | 10.1002/cbin.70002 | 2025-02-13 | CELL BIOLOGY INTERNATIONAL | 3.1 | Yuan Jia, Yi Qin, Feng-Lai Yuan, Jie-Hong Shen |
| Enhancing Antituberculosis Treatment Nanoparticles Encapsulated with Catalase and Levofloxacin Under Ultrasound Stimulation: A 3D Spheroid Study | 10.1021/acs.molpharmaceut.4c00748 | 2025-01-07 | MOLECULAR PHARMACEUTICS | 4.5 | Jiajun Guo, Yan Qiu, Can Hu, Yuchao Cao, Dairong Li, Yonghong Du |
| Mollugin inhibits IL-1β production by reducing zinc finger protein 91-regulated Pro-IL-1β ubiquitination and inflammasome activity | 10.1016/j.intimp.2024.113757 | 2024-12-06 | INTERNATIONAL IMMUNOPHARMACOLOGY | 4.8 | Lei Song, Yi Tai, Jia Xuan Li, Shen Cao, Jing Han, Xin Zhe Liu, Sheng Cao, Ming Yue Li, Hong Xiang Zuo, Yue Xing, Juan Ma, Xuejun Jin |
| Cinobufagin inhibits M2‑like tumor‑associated macrophage polarization to attenuate the invasion and migration of lung cancer cells | 10.3892/ijo.2024.5690 | 2024-09-11 | INTERNATIONAL JOURNAL OF ONCOLOGY | 4.5 | Ying Sun, Yunfeng Lian, Xue Mei, Jinchan Xia, Long Feng, Jianfeng Gao, Huaming Xu, Xiaoyan Zhang, Huitong Yang, Xu Hao, Yilin Feng |
| Breast cancer colonization by Malassezia globosa accelerates tumor growth | 10.1128/mbio.01993-24 | 2024-09-05 | mBio | 5.1 | Miao-Miao Liu, Hui-Hui Zhu, Jie Bai, Zi-Ye Tian, Yu-Jing Zhao, Teun Boekhout, Qi-Ming Wang |
| LncRNA TRPM2-AS promotes endometrial carcinoma progression and angiogenesis via targeting miR-497-5p/SPP1 axis | 10.1186/s11658-024-00612-7 | 2024-07-02 | CELLULAR & MOLECULAR BIOLOGY LETTERS | 9.2 | Ma Hanbo, Weng Fengyun, Tong Xiaowen, Li Huaifang, Yao Yinan, Yuan Jiangjing |
| TMEM205 induces TAM/M2 polarization to promote cisplatin resistance in gastric cancer | 10.1007/s10120-024-01517-2 | 2024-06-08 | Gastric Cancer | 6.0 | Fu Qiang, Wu Xuwei, Lu Zhongqi, Chang Ying, Jin Quanxin, Jin Tiefeng, Zhang Meihua |
| Single-cell analyses reveal the metabolic heterogeneity and plasticity of the tumor microenvironment during head and neck squamous cell carcinoma progression | 10.1158/0008-5472.CAN-23-1344 | 2024-05-08 | CANCER RESEARCH | 12.5 | Meng Xiaoyan, Zheng Yang, Zhang Lingfang, Liu Peipei, Liu Zhonglong, He Yue |
| Identification of shared potential diagnostic markers in asthma and depression through bioinformatics analysis and machine learning | 10.1016/j.intimp.2024.112064 | 2024-04-11 | INTERNATIONAL IMMUNOPHARMACOLOGY | 4.8 | Hui Jiang, Chang-yong Fu |
| Apelin Prevents and Alleviates Crystalline Silica-induced Pulmonary Fibrosis via Inhibiting Transforming Growth Factor Beta 1-triggered Fibroblast Activation | 10.7150/ijbs.81436 | 2023-07-31 | International Journal of Biological Sciences | 9.2 | Shen Jianling, Feng Jiayin, Wu Zhijia, Ou Yushi, Zhang Qing, Nong Qiying, Wu Qifeng, Li Cong, Tan Xiaohui, Ye Meng, Gao Zhongxiang, Zhang Ying, Liang Weihui, Xia Lihua, Qin Yiru, Huang Yongshun, Zhao Na, Hu Shijie |
| BushenHuoxue decoction suppresses M1 macrophage polarization and prevents LPS induced inflammatory bone loss by activating AMPK pathway. | 10.1016/j.heliyon.2023.e15583 | 2023-04-19 | Heliyon | 4.0 | Shuangshuang Chen, Lihong Tao, Feng Zhu, Zhifang Wang, Qi Zhuang, Yajun Li, Yunshang Yang, Chengcheng Feng, Haiwei Shi, Jiandong Shi, Like Zhu, Long Xiao, Dechun Geng, Zhirong Wang |
| CtrA activates the expression of glutathione S-transferase conferring oxidative stress resistance to Ehrlichia chaffeensis | 10.3389/fcimb.2022.1081614 | 2022-12-12 | Frontiers in Cellular and Infection Microbiology | 6.1 | Liang Qi’an, Yan Jiaqi, Zhang Shuwen, Yang Nan, Li Meifang, Jin Yongxin, Bai Fang, Wu Weihui, Cheng Zhihui |
| Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawasaki disease | 10.3389/fimmu.2022.922868 | 2022-08-02 | Frontiers in Immunology | 8.8 | Manli Guo, Shunyang Fan, Qian Chen, Cuiping Jia, Miaoyun Qiu, Yun Bu, Wai Ho Tang, Yuan Zhang |
| Cardiac glycosides from the roots of Streblus asper Lour. with activity against Epstein-Barr virus lytic replication | 10.1016/j.bioorg.2022.106004 | 2022-07-09 | BIOORGANIC CHEMISTRY | 5.3 | Jing Cai, Bo-Dou Zhang, Yu-Qi Li, Wan-Fang Zhu, Toshihiro Akihisa, Takashi Kikuchi, Jian Xu, Wen-Yuan Liu, Feng Feng, Jie Zhang |
| Integrated DNA and RNA sequencing reveals early drivers involved in metastasis of gastric cancer | 10.1038/s41419-022-04838-1 | 2022-04-21 | Cell Death & Disease | 9.7 | Zhang Jieyun, Liu Fatao, Yang Yanan, Yu Nuoya, Weng Xiaoling, Yang Yue, Gong Zhe, Huang Shenglin, Gan Lu, Sun Sijie, Zhang Xiaowei, Gong Yiwei, Liu Yun, Guo Weijian |
| MicroRNA-122-5p regulates coagulation and inflammation through MASP1 and HO-1 genes | 10.1016/j.meegid.2022.105268 | 2022-03-12 | INFECTION GENETICS AND EVOLUTION | 4.4 | Huijuan Wang, Chunfang Zhang, Chao Zhang, Yishan Wang, Kan Zhai, Zhaohui Tong |
| Trop2 binding IGF2R induces gefitinib resistance in NSCLC by remodeling the tumor microenvironment | 10.7150/jca.57711 | 2021-07-03 | Journal of Cancer | 4.2 | Xia Sun, Lizhou Jia, Tengqi Wang, Yulian Zhang, Wei Zhao, Xiangcheng Wang, Hao Chen |
相关实验
我养过皮肤成纤维细胞和THP-1细胞。皮肤成纤维细胞是贴壁生长的。THP-1细胞是悬浮的。由于我们实验室养细胞的时间也不是很长，所以也只能说说自己平时的操作了。先说皮肤成纤维细胞。当细胞铺满瓶底，也就是细胞与细胞之间没有间隙时，就可以传代了。一般十天左右传一代。先吸弃旧培养液，用D-Hanks液洗两遍，再加入0.25%的胰酶，加入的量以能覆盖瓶底为准。加入后轻轻摇晃培养瓶使液体覆盖瓶底，然后静置两分钟左右，最好是能在显微镜下观察，当细胞之间出现间隙且有一部分细胞呈现圆形后即可。吸去胰酶，加入含
polymorphic Y chromosome-specific short tandem repeats (STRs) have been described and a set of 9 loci were selected, considered as the minimal haplotype included in the forensic databases, Y-STR Haplotype Reference Databases, the largest now available online
Constructing STR Multiplex Assays
Multiplex polymerase chain reaction (PCR) refers to the simultaneous amplification of multiple regions of deoxyribonucleic acid (DNA) using PCR. Commercial short tandem repeat (STR) assays that can coamplify as many as 16 different loci
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人单核细胞白血病细胞；THP-1(STR)
￥1400 - 1700
