- 询价
- 沪震生物
- 进口/国产
- hz263Bo01
- 2025年07月13日
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- 文献和实验
- 技术资料
- 保存条件：
-20℃
- 保质期：
12个月
- 英文名：
Recombinant Creatine Kinase, Mitochondrial 1A (CKMT1A)
- 库存：
100
- 供应商：
上海沪震
FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
Organism species Bos taurus; Bovine (Cattle)
Product No. RPA263Bo01
Source Prokaryotic expression
Host E.coli
Purity > 95%
UOM 50ug
Predicted Molecular Mass n/a
Predicted isoelectric point n/a
Applications SDS-PAGE; WB; ELISA; IP.
Endotoxin Level <1.0EU per 1µg (determined by the LAL method)
Subcellular Location n/a
Residues n/a
Formulation Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
USAGE
Reconstitute in sterile PBS, pH7.2-pH7.4.
STORAGE AND STABILITY
线粒体肌酸激酶1A(CKMT1A)重组蛋白Storage: Avoid repeated freeze/thaw cycles. Store at 2-8oC for one month. Aliquot and store at -80oC for 12 months.
Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37oC for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
About the MARKER (complimentary)
Effective Size Range: 10kDa to 70kDa.
Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and 70kDa.
Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at double intensity to make location and size approximation of proteins of interest quick and easy.
线粒体肌酸激酶1A(CKMT1A)重组蛋白Ready-to-use: No need to heat, dilute or add reducing agents before use.
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PRMT5活性；靶向PRMT5可诱导LKB1缺陷型肺癌细胞发生衰老，表现为CDKN1A上调和DNA损伤累积。研究团队进一步提出并验证了PRMT5抑制剂GSK3326595与衰老清除剂Navitoclax联合用药策略，在LKB1缺陷型肺癌体内外模型中显著抑制肿瘤进展。该研究拓展了PRMT5抑制剂的适用人群至LKB1缺失型肿瘤，为临床治疗提供了新方向。 05 靶点：PGRN/GRN 应用：泰国伯克霍尔德菌脓毒症治疗的潜在靶点 来源：PGRN
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