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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human recombinant CYP1A2
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H
- 宿主:
Rabbit
- 应用范围:
E, WB, IHC
- 浓度:
见详细说明信息
- 靶点:
CYP1A2
- 抗体英文名:
CYP1A2 Antibody
- 抗体名:
CYP1A2 Antibody
- 规格:
0.1 mg
CYP1A2 Antibody产品详细介绍:
| 产品名称: | CYP1A2 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 254539 |
| 规格: | 0.1 mg |
| 产品描述: | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, cytochrome P450 1A2 (CYP1A2) is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. CYP1A2 is most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by CYP1A2 in the liver through an initial N3-demethylation. It also acts in the metabolism of aflatoxin B1 and acetaminophen. CYP1A2 participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. It catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | Human recombinant CYP1A2 |
| 适用物种: | H |
| 应用范围: | E, WB, IHC |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别名: | CYP1A2; Cytochrome P450 1A2; CYPIA2; cytochrome P(3)450; P450-P3 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验人 CYP1A2酶联免疫 分析 试剂 盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中 CYP1A2 的含量。 实验原理 : 本试剂盒应用双抗体夹心法测定 标本 中 人 CYP1A2 水平。用纯化的 人 CYP1A2 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 CYP1A2 ,再与HRP 标记的 CYP1A2 抗体结合,形成抗体- 抗原 - 酶标抗体复合物 ,经过彻底
Bradfield Lab, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison Medical School http://mcardle.oncology.wisc.edu/bradfield/Cyp1a2-genotyping.html This protocol uses Ampitaq Gold from Perkin-Elmer
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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