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- 详细信息
- 技术资料
- 免疫原:
Recombinant neuronal NOS fragment(amino acids 1-181) from rat brain.
- 亚型:
Mouse IgG1
- 形态:
液态
- 保存条件:
保存于-20℃
- 克隆性:
单克隆
- 标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
- 适应物种:
Goat, Hu, Pig, Rat
- 保质期:
按说明书条件可保存1-2年
- 抗原来源:
见详细说明资料
- 目录编号:
PL0401270
- 级别:
超纯
- 库存:
大量
- 供应商:
华拓生物
- 宿主:
Mouse
- 应用范围:
WB: 1:100-500
- 浓度:
1mg/ml
- 靶点:
NOS1
- 抗体英文名:
NOS1 Antibody
- 抗体名:
NOS1单克隆抗体
- 规格:
0.1ml
NOS1 Antibody
Cat#:PL0401270
Isotype:Mouse IgG1
Immunogen:Recombinant neuronal NOS fragment(amino acids 1-181) from rat brain.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Nitric Oxide Synthase 1(NOS1,neuronal NOS,nNOS1) is a messenger molecule, mediating the effect of endothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages, and playing a part in neuronal communication in the brain. It may be involved in neuronal cell death and damage in neurological illness. nNOS1 localized to the 12q24.2 region of human chromosome 12. It splice variant, expressed in testis, that encodes an NH2-terminal truncated protein of 1098 amino acids. nNOS cDNA clones were shown to contain different 5' terminal exons spliced to a common exon 2. Genomic cloning and sequence analysis demonstrate that the unique exons are positioned within 300 bp of each other but separated from exon 2 by an intron that is at least 20 kb in length. The neuronal isoform of nitric oxide synthase is highly expressed in mammalian skeletal muscle, it suggested a specific role for NOS1 in the local metabolic inhibition of alpha-adrenergic vasoconstriction in active skeletal muscle. The novel gaseous neuromediator nitric oxide is though to play an important role in development and plasticity.
Alternate Names:
NOS;bNOS;nNOS;IHPS1;N-NOS;NC-NOS;Neuronal NOS;Peptidyl-cysteine S-nitrosylase NOS1.
Specificity Reaction:Goat, Hu, Pig, Rat
Application Notes:WB: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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NOS1 Antibody
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