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- 详细信息
- 技术资料
- 免疫原:
peptide corresponding to a sequence at the C-terminus of human CYP11A1.
- 亚型:
Rabbit Polyclonal IgG
- 形态:
液态
- 保存条件:
保存于-20℃
- 克隆性:
多克隆
- 标记物:
无标记(PLlabs可供应生物素、酶、荧光素标记的抗体)
- 适应物种:
Hu
- 保质期:
按说明书条件可保存1-2年
- 抗原来源:
见详细说明资料
- 目录编号:
PL0402338
- 级别:
超纯
- 库存:
大量
- 供应商:
华拓生物
- 宿主:
Rabbit
- 应用范围:
WB: 1:100-500 IHC: 1:500-1000
- 浓度:
1mg/ml
- 靶点:
CYP11A1
- 抗体英文名:
CYP11A1 Antibody
- 抗体名:
CYP11A1抗体
- 规格:
0.1ml
CYP11A1 Antibody
Cat#:PL0402338
Isotype:Rabbit Polyclonal IgG
Immunogen:peptide corresponding to a sequence at the C-terminus of human CYP11A1.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
CYP11A1(Cytochrome p450, family 11, subfamily A, polypeptide 1), also called CYTOCHROME P450SCC, CYTOCHROME P450C11A1 or CYP11A, is a mitochondrial enzyme associated with the conversion of cholesterol to pregnenolone. CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The CYP11A1 gene is mapped on 15q24.1. Expression of the CYP11A1 gene may play a role in skin physiology and pathology and that cutaneous proopiomelanocortin activity may be autoregulated by a feedback mechanism involving glucocorticoids synthesized locally by Slominski et al. Using in vitro studies, CYP11A1 catalyzed the side-chain cleavage of 7-dehydrocholesterol to form 7-dehydropregnenolone. In addition, CYP11A1 catalyzed the metabolism of biologically inert vitamin D3, which is formed from 7-dehydrocholesterol, to form 2 hydroxylated products, 20-hydroxyvitamin D3 and 20, 22-dihydroxyvitamin D3.
Alternate Names:
Cholesterol 20 22 desmolase antibody;Cholesterol desmolase antibody;Cholesterol monooxygenase(side chain cleaving) antibody;Cholesterol side chain cleavage enzyme antibody;Cholesterol side chain cleavage enzyme mitochondrial antibody;Cholesterol side-chain cleavage enzyme antibody;CP11A_HUMAN antibody.
Specificity Reaction:Hu
Application Notes:WB: 1:100-500 IHC: 1:500-1000
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素(FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体,欢迎大家咨询订购。
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CYP11A1 Antibody
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