Exosome Component 6 (EXOSC6) (

Exosome Component 6 (EXOSC6) (N-Term) 抗体抗原
Exosome Component 6 (EXOSC6)
别名 exosc6, RAR-gamma, id:ibd1130, wu:fe17d05, zgc:110071, EAP4, MTR3, Mtr3p, hMtr3p, p11, 2610510N21Rik, C76919, Mtr3
抗原表位
其他选择 N-Term
适用
其他选择 犬, 大鼠, 小鼠, 牛, 人
宿主
其他选择 兔
克隆类型
多克隆
标记
其他选择 非结合性
应用范围
其他选择 免疫组织化学（IHC）, Western Blotting (WB)
Pubmed 找到1个引用
规格 100 μg
发货至 中国 (更改)
发货时间 9至12个工作日
产品编号 yb184073
产品细节 Exosome Component 6 (EXOSC6) (N-Term) 抗体
免疫原 Synthetic peptide directed towards the N terminal of human EXOSC6
序列 MPGDHRRIRG PEESQPPQLY AADEEEAPGT RDPTRLRPVY ARAGLLSQAK
预测反应 Bovine : 92 %, Rat : 92 %
产品特性 This is a rabbit polyclonal antibody against EXOSC6. It was validated on Western Blot and immunohistochemistry.
纯化方法 Protein A purified
目标详细情况 Exosome Component 6 (EXOSC6) (N-Term) 抗体
别名 EXOSC6
背景 EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
分子量 30 kDa
基因ID 118460
NCBI登录号 NM_058219, NP_478126
UniProt Q5RKV6
研究领域 Chromatin and Nuclear Signaling, DNA/RNA
使用细节 Exosome Component 6 (EXOSC6) (N-Term) 抗体
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明
Antigen size: 272 AA
限制 仅限研究用
贮存及处理 Exosome Component 6 (EXOSC6) (N-Term) 抗体
状态 Lyophilized
溶解方式 Add 100 µL of distilled water.
浓度 1 mg/mL
缓冲液 PBS buffer with 2 % sucrose
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20 °C