G蛋白偶联受体109A抗体

G蛋白偶联受体109A抗体产品类别

兔抗人、大、小鼠GPR109A抗体

产品价格

0.2ml/1480元

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

G蛋白偶联受体109A抗体产品介绍

Niacin receptor 1 (pumma gamma) acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis.
AltName:
Niacin receptor 1;
Nicotinic acid receptor;
G-protein coupled receptor 109;
G-protein coupled receptor HM74;
Protein PUMA-G.
G蛋白偶联受体109A抗体