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- 克隆性：
单克隆
- 抗体英文名：
Anti-KLK10(Kallikrei
- 抗体名：
激肽释放酶10抗体
Kallikrein 10 is a trypsin-like serine proteinase. Originally described from a subtractive library looking for genes that were down-regulated in breast cancer, kallikrein 10 was thought to be epithelial cell specific. Kallikrein 10 is reported to be up regulated in pancreatic cancer and ovarian cancer, but down regulated in testicular cancer and breast cancer, perhaps due to differential hormonal regulation, or tissue specificities. Breast cancer patients that had elevated kallikrein 10 had a worse prognosis, leading to speculation that kallikrein 10 might be protective in breast cancer, similar to the argument put forth for kallikrein 3 in prostate cancer. Kallikrein 10 is found in high levels in the pancreas and in lower levels in the tonsils, esophagus, skin, brain, testis and ovary. Biological fluids (breast milk, serum, seminal plasma, urine) contain kallikrein 10, the highest levels found in milk. The cerebral spinal fluid (CSF) contains Kallikrein 10, and was reported to be elevated in patients with Alzheimer’s disease. Endogenous inhibitors include kallistatin, protein-C inhibitor and 1-proteinase inhibitor, although Kallikrein 10 can be found complexed to a number of different proteinase inhibitors.
mol wt:31kDa
Other Aliases:
Kallikrein 10; Breast normal epithelial cell associated serine protease; Kallikrein related peptidase 10 ; KLK 10; KLK10; NES 1; NES1; Normal epithelial cell specific 1; Protease serine like 1; PRSS L1; PRSSL 1; PRSSL1
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文献和实验人激肽释放酶8(KLK-8) 酶联免疫分析（ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中激肽释放酶8(KLK-8) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人激肽释放酶 8(KLK-8) 水平。用纯化的人激肽释放酶 8(KLK-8) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入激肽释放酶 8(KLK
人激肽释放酶10 （KLK 10 ） 酶联免疫分析（ ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中激肽释放酶10 （KLK 10 ）的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中 人激肽释放酶 10 （ KLK 10 ） 水平。用纯化的 人激肽释放酶 10 （ KLK 10 ）抗体 包被微孔板，制成固相抗体，往包被单抗的微孔中
与激肽生成有关的蛋白酶。EC3． 4． 21． 8。广泛存在于血浆和组织中。可从狗的胰脏中提取出来，但从人、牛、马、狗、猫等的腮腺、颌下腺、舌下腺等也能获得同样的物质。虽不引起正常动物的血糖量的变化，但具有使切除胰脏的狗或人的糖尿病患者的血糖量降低的作用。它与胰岛素是不同的物质，口服也有效。
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