激肽释放酶10抗体

激肽释放酶10抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

激肽释放酶10抗体产品介绍

KLK10是组织激肽释放酶基因家族的重要成员,是当前研究较热的肿瘤生物学标志物之一,在多种与内分泌相关的肿瘤中有较特异性的表达。
Kallikrein 10 is a trypsin-like serine proteinase. Originally described from a subtractive library looking for genes that were down-regulated in breast cancer, kallikrein 10 was thought to be epithelial cell specific. Kallikrein 10 is reported to be up regulated in pancreatic cancer and ovarian cancer, but down regulated in testicular cancer and breast cancer, perhaps due to differential hormonal regulation, or tissue specificities. Breast cancer patients that had elevated kallikrein 10 had a worse prognosis, leading to speculation that kallikrein 10 might be protective in breast cancer, similar to the argument put forth for kallikrein 3 in prostate cancer. Kallikrein 10 is found in high levels in the pancreas and in lower levels in the tonsils, esophagus, skin, brain, testis and ovary. Biological fluids (breast milk, serum, seminal plasma, urine) contain kallikrein 10, the highest levels found in milk. The cerebral spinal fluid (CSF) contains Kallikrein 10, and was reported to be elevated in patients with Alzheimer’s disease. Endogenous inhibitors include kallistatin, protein-C inhibitor and 1-proteinase inhibitor, although Kallikrein 10 can be found complexed to a number of different proteinase inhibitors.
mol wt:31kDa
Other Aliases:
Kallikrein 10; Breast normal epithelial cell associated serine protease; Kallikrein related peptidase 10 ; KLK 10; KLK10; NES 1; NES1; Normal epithelial cell specific 1; Protease serine like 1; PRSS L1; PRSSL 1; PRSSL1

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zk-1530zk Slc4a7/Nbcn1(solute carrier family 4, sodium bicarbonate cotransporter, member 7)碳酸氢钠协同转运蛋白4-A7抗原
zk-1298zk Smac/DIABLO(the second mitochondrial activator of caspase)线粒体促凋亡蛋白抗原
zk-0699zk SLC33A1(Acetyl-coenzyme A transportor 1)乙酰辅酶A转运蛋白1抗原
zk-0856zk SLC34A2/NaPi-2b(Solute carrier family 34 member 2)磷酸钠协同转运蛋白抗原
zk-2034zk SMN1(survival of motor neuron 1)运动神经元生存蛋白1抗原
zk-2224zk phospho-Smad2(p-Ser465)petide磷酸化Smad2抗原
zk-0585zk Smad4(Mothers against decapentaplegic homolog 4)Smad4抗原
zk-0566zk Smad7(Mothers against decapentaplegic homolog 7)Smad 7(多肽)
zk-0457zk phosphor-SMAD(p-Ser425)、phosphor-Mothers against decapentaplegic磷酸化SMAD(p-Ser425)抗原
zk-1131zk SNAP-25 (synaptosomal-associated protein 25)突触相关膜蛋白25抗原
zk-1371zk SnailSnail蛋白抗原
zk-0580zk Socs 3 (suppressor of cytokine signaling 3)细胞因子信号传导抑制蛋白3抗原
zk-1079zk SOD1(superoxide-dimutase-1)超氧化物歧化酶1抗原
zk-1080zk SOD2 (superoxide-dimutase-2)超氧化物歧化酶2抗原
zk-1132zk Somatostatin/GRIH生长抑素抗原
zk-0523zk Sox2胚胎干细胞关键蛋白
zk-0975zk TSFP1/SP1(transcription factor Sp1)SP1转录生长因子抗原
zk-1133zk SPARC (secreted protein acidic and rich in cysteine)富含半胱氨酸的酸性分泌蛋白抗原
zk-1401zk SRF(Serum response factor)血清应答因子抗原
zk-1402zk SREBP-1(Sterol Regulatory Element Binding Protein-1)固醇调节元件结合蛋白1抗原
zk-1381zk AKAP12A/SSeCKS peptide丝氨酸抑制蛋白激酶C底物抗原
zk-1702zk Fut4/CD15/SSEA-1(Stage-specific embryonic surface antigen 1)阶段特异性胚胎表面抗原-1抗原
zk-1137zk SSTR1 (somatostatin receptor 1)生长抑素受体1(SSTR1)抗原
激肽释放酶10抗体