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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human Protein-arginine deiminase type-4 protein (1-250AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q9UM07
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
- 浓度:
>95%,Antigen Affinity Purified
- 靶点:
PADI4
- 抗体英文名:
PADI4 Antibody
- 抗体名:
Protein-arginine deiminase type-4 antibody
- 规格:
100μl/50μl/20μl
| 规格: | 100μl | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥880.0 |
| 规格: | 20μl | 产品价格: | ¥440.0 |
保存缓冲液
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. Citrullinates histone H1 at \'Arg-54\' (to form H1R54ci), histone H3 at \'Arg-2\', \'Arg-8\', \'Arg-17\' and/or \'Arg-26\' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at \'Arg-3\' (to form H4R3ci). Acts as a key regulator of stem cell maintenance by mediating citrullination of histone H1: citrullination of \'Arg-54\' of histone H1 (H1R54ci) results in H1 displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance. Promotes profound chromatin decondensation during the innate immune response to infection in neutrophils by mediating formation of H1R54ci. Citrullination of histone H3 prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at \'Arg-2142\', which favors its interaction with NCOA2/GRIP1.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验双特异抗体(Bispecific antibody)的简介和制作方法
contain two identical antigen-binding arms and a constant fragment, (Fc)g. The Fc part enables the antibody to function as an adaptor protein, linking antibody-bound cells to immune cells bearing Fcg receptors. Because there are different Fcg receptors
抗子宫内膜抗体(endomethal antibody,EMAb)检测
子宫内膜抗体(endomethal antibody,EMAb)是子宫内膜异位病患者受到异位内膜的刺激,或经血逆流等因素导致免疫应答紊乱产生的一种自身抗体,并与子宫内膜中靶抗原结合,在补体参与下,引起子宫内膜免疫病理损伤,影响孕卵着床,也容易发生早期流产。目前检测EMAb的方法有间接免疫荧光法(1FT)、双向免疫扩散法(1D)、间接血凝法(PHA)及ELISA法等。IFF法需刮取子宫内膜制备抗原片,并需一定设备
人抗肽酰基精氨酸脱亚胺酶4(PADI4)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人 抗肽酰基精氨酸脱亚胺酶4 (PADI4)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 PADI4 单抗包被于酶标板上,标准品和样品中的 PADI4与单抗结合,加入生物素化的抗人
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