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Recombinant Human Interferon-b

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  • ¥1680 - 3988
  • 美国ATCC
  • 美国/中国
  • 2025年07月13日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      大量

    • 供应商

      钰博生物

    • 细胞类型

      复苏

    • 组织来源

      见说明书

    • 物种来源

      人、大鼠、小鼠、、、、

    • 免疫类型

      请咨询销售人员

    • 细胞形态

      上皮样;多角形

    • 是否是肿瘤细胞

      见说明书

    • 器官来源

      见说明书

    • 运输方式

      干冰运输or活细胞运输

    • 年限

      见说明书

    • 生长状态

      贴壁生长

    Recombinant Human Interferon-beta 1a
    Synonyms Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB, IFN-b 1a ,MGC96956.
    Introduction Interferon-beta has antiviral, antibacterial and anticancer activities.
    Description Interferon-beta 1a Human Recombinant produced in CHO (Chinese Hamster Ovarian) cells is a single, glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of 22500 Dalton.
    IFN-beta1a is purified by proprietary chromatographic techniques.
    Source CHO (Chinese Hamster Ovarian) cells.
    Recombinant Human Interferon-beta 1aFormulation Lyophilized from 1mg/10ml solution containing 91 mg Human Albumin, and 620 mg mannitol, and 9 mg Sodium Acetate.
    Solubility It is recommended to reconstitute the lyophilized Interferon beta 1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
    Stability Lyophilized Interferon-beta 1a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-Beta1a should be stored at 4°C between 2-7 days and for future use below -18°C.
    Please prevent freeze-thaw cycles.
    Recombinant Human Interferon-beta 1aPurity Greater than 98.0% as determined by(a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.
    Amino acid sequence MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN.
    Biological Activity The specific activity as determined in a viral resistance assay (human "Wish" cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 270MIU/mg.
    Referencess Title:Interferon-β induces apoptosis in human SH-SY5Y neuroblastoma cells through activation of JAK–STAT signaling and down-regulation of PI3K/Akt pathway.
    Publication:Article first published online: 11 NOV 2010 DOI:10.1111/j.1471-4159.2010.07046.x
    Recombinant Human Interferon-beta 1aUsage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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