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- 文献和实验
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- 克隆性:
单克隆
- 抗体英文名:
Anti-KLK9(Kallikrein
- 抗体名:
激肽释放酶9抗体
组织KLK是一个大的基因家族,主要分布在肺、肾、血管、脑、肾上腺组织,为一种中等大小的糖蛋白。
Kallikrein 9, also known as Kallikrein-Like 3 (KLK-L3), is a chymotrypsin-like serine proteinase. Kallikrein 9 was discovered as the locus for kallikreins on chromosome 19 was more fully mapped and found by similarity to the other tissue kallikreins. Kallikrein 9 has been found in the ovary, thymus, testis, prostate, skin, breast and neuronal tissues and is made by many cell lines in culture. Kallikrein 9 levels in breast cancer and uterine cancer patients have been reported to drop as the disease progresses, thus hK9 might be considered a favorable prognostic marker. Different splice variants of hK9 have been reported, although it is not yet known if they produce functional proteins. The full length Kallikrein 9 encodes for a 250 amino acid protein, with a predicted mass of 27.5 kDa and a pI of 7.53. The 234 amino acid form predicts a protein of 26 kDa with a pI of 9.76 and this quite basic pI might give the shorter form a very different function or localization. The shorter sequence also diverges before the catalytic serine residue, making it unlikely to be proteolytically active. Pre-pro-kallikrein 9 has the 17 amino acid signal sequence is removed before secretion, and the Pro-kallikrein 9 is activated to Kallikrein 9 by removal of the 5 amino acid propeptide domain.
mol wt:28kDa
Other Aliases:
Kallikrein 9; kallikrein-like protein 3; KLK-L3; Kallikrein 8; Kallikrein 9; Kallikrein L3; Kallikrein Like 3; kallikrein related peptidase 9;Kallikrein8;Kallikrein9; KLK 8; KLK 9;KLK L3; KLK8; KLK9; KLKL 3; KLKL3
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文献和实验人激肽释放酶8(KLK-8) 酶联免疫分析(ELISA ) 试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中激肽释放酶8(KLK-8) 的 含量。 实验原理: 本试剂盒应用双抗体夹心法测定标本中人激肽释放酶 8(KLK-8) 水平。用纯化的人激肽释放酶 8(KLK-8) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入激肽释放酶 8(KLK
与激肽生成有关的蛋白酶。EC3. 4. 21. 8。广泛存在于血浆和组织中。可从狗的胰脏中提取出来,但从人、牛、马、狗、猫等的腮腺、颌下腺、舌下腺等也能获得同样的物质。虽不引起正常动物的血糖量的变化,但具有使切除胰脏的狗或人的糖尿病患者的血糖量降低的作用。它与胰岛素是不同的物质,口服也有效。
人激肽释放酶1(KLK-1) 酶联免疫分析(ELISA ) 试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本中激肽释放酶1(KLK-1) 的 含量。 实验原理: 本试剂盒应用双抗体夹心法测定标本中人激肽释放酶 1(KLK-1) 水平。用纯化的人激肽释放酶 1(KLK-1) 抗体包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入激肽释放酶 1(KLK
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