端粒体复制结合因子1抗体

端粒体复制结合因子1抗体产品介绍

TRBF1端粒体复制结合因子1，在细胞周期的过程中都有该蛋白的存在，可抑制端粒酶的活性，限制染色体顶端的延长。端粒体复制结合因子1位于端粒体顶端，是端粒体核酸蛋白复合物的组成部分。


This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq].
mol wt:48kDa
Other Aliases:
Telomeric repeat binding factor 1; FLJ41416; hTRF1-AS; t-TRF1; TRF; TRF1; NIMA-interacting 1; NIMA interacting protein 2; PIN 2; PIN2; Telomeric protein Pin2; Telomeric protein Pin2/TRF1; Telomeric repeat binding factor (NIMA interacting) 1; Telomeric repeat binding protein 1; TERF 1; TERF1; TRBF 1; TRBF1; TRF 1; TTAGGG repeat binding factor 1.

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