Tau Phosphorylation Site-Speci
fic Antibody Sampler (Containing Tau pS199, pT205, pT231, pS262, pS356,pS396, pS404, pS409, pS422 Rabbit Polyclonal & Tau [TAU-5] Monoclonal Antibodies, Unconjugated)- 询价
- 1 kit
- 美国
- HH-44779G
- 2025年07月13日
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- 供应商：
南京赛泓瑞
- 规格：
25 UG BIOSOURCE (TM)
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文献和实验14-3-3 is a potent inhibitor of protein kinase C, but the N-terminal domain does not inhibit PKC activity. Site-specific mutagenesis of several regions in the tau isoform of 14-3-3, including the mutation of a putative pseudosubstrate site
that the negative charge onthe TDZD heterocycle recognizes the oxyanion-binding site ofthe enzyme (24) , thereby blocking its ability to recognize prephosphorylatedsubstrates. The last and most specific methodto inhibit cellular GSK-3 kinase activity is depletion
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
may be due to growth factor inhibition being mediatedthrough N-terminal phosphorylation of GSK3, resulting ininhibition of primed substrates, and Wnt inhibition focussing ona specific GSK3-containing complex. In addition, growth factorsregulate both GSK3a and GSK
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