Mouse CPA1抗体

Mouse CPA1抗体产品信息

免疫原 :
Recombinant mouse CPA1 protein ( Catalog#50448-M08H )
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, human cell-derived, recombinant mouse CPA1 ( rM CPA1 ; Catalog#50448-M08H ; NP_079626.2 ; Met 1 - Tyr 419 ). CPA1 specific IgG was purified by mouse CPA1 affinity chromatography.
Mouse CPA1抗体Background
Mouse Carboxypeptidase A1（CPA1）is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of pancreatic pro-carboxypeptidase A have been isolated.
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