CD59 / CD59A / MAC / IP抗体

CD59 / CD59A / MAC / IP抗体产品信息

免疫原 :
Recombinant Rat CD59 / CD59A / MAC / IP protein (Catalog#80299-R08H)
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
Produced in rabbits immunized with purified, recombinant Rat CD59 / CD59A / MAC / IP (rR CD59 / CD59A / MAC / IP; Catalog#80299-R08H; P27274; Met1-Asn100). Total IgG was purified by Protein A affinity chromatography.
CD59 / CD59A / MAC / IP抗体 Background
CD59 glycoprotein, also known as 20 kDa homologous restriction factor, HRF20, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D).
CD59 / CD59A / MAC / IP抗体相关产品如下：
hz-2654R LTB4-R1/BLTR白三烯B4受体1抗体
hz-2656R LIR-6白细胞免疫球蛋白样受体6抗体
hz-2646R LAG-3/CD223淋巴细胞活化基因-3抗体
hz-2647R LAIR-1白细胞相关免疫球蛋白样受体1抗体
hz-2650R Langerin/CD207白细胞分化抗原CD207抗体
hz-2655R LTB4-R2白三烯B4受体2抗体
hz-2648R LAIR-2白细胞相关免疫球蛋白样受体2抗体
hz-6069R LLGL1相似肿瘤抑制基因HUGL抗体
hz-6319R IL-1 Beta白介素1β抗体
hz-0814R Beta-lactoglobulinβ-乳球蛋白抗体
hz-12150R LPPR1脂质磷酸磷酸酶相关蛋白1/可塑性相关基因3抗体
hz-12141R LRFN1神经突触粘附样分子1抗体
hz-9327R LRCH1富含亮氨酸重复家庭蛋白1抗体
hz-9330R LRCH4富含亮氨酸重复家庭蛋白4抗体
hz-0109R Leptin receptor(long)瘦素受体抗体（长）
hz-1058R LIF白血病抑制因子抗体
hz-1177R Lingo-1Nogo受体反应蛋白抗体
hz-0738R Livin凋亡抑制蛋白抗体
hz-0821R laminin层粘连蛋白抗体
hz-0759R Lpin1 proteinLpin1 抗体
hz-0760R Lpin1 proteinLpin1 抗体
hz-0816R Lysozyme溶菌酶抗体
hz-0484R Iumbrokinase蚓激酶抗体
hz-0409R Leptin瘦素抗体
hz-0410R Leptin receptor瘦素受体抗体
hz-0109M Leptin receptor(long)瘦素受体抗体（长）
hz-9708R LCE1A晚期包膜蛋白1抗体
hz-6862R LANPL富含亮氨酸样酸性核蛋白抗体
hz-9709R LCE2B晚期包膜蛋白2B抗体
hz-9711R LIPK脂肪酶家庭成员K抗体
hz-1902R Stathmin白血病相关蛋白18/癌蛋白18抗体
hz-2035R LIS1无脑回的致病基因LIS1抗体
hz-2556R LAMP3溶酶体相关膜蛋白3抗体
hz-1758R L-ENK亮氨酸脑啡肽抗体
hz-2912R LC3B/MAP LC3β/MAP1A自噬微管相关蛋白轻链3抗体
hz-11780R LMX1b指甲髌骨综合征相关蛋白NPS1抗体
hz-4843R LC3B自噬微管相关蛋白轻链β3抗体
hz-8361R LRRC59LRRC59蛋白抗体
hz-8362R LRRC41LRRC41蛋白抗体
hz-6431R LHR促黄体生成素受体抗体
hz-11131R alpha Lactalbumin乳清蛋白α抗体
hz-11132R Lamin B2核纤层蛋白B2抗体
hz-1086R Laminin alpha 5层粘蛋白α5抗体
hz-0619R L-CitrullineL-瓜氨酸抗体