DLL1抗体

DLL1抗体产品信息

免疫原 :
Recombinant Mouse DLL1 protein (Catalog#50522-M08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
036
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse DLL1 (rM DLL1; Catalog#50522-M08H; NP_031891.2; Met 1-Gln 516).
DLL1抗体 Background
Delta-like protein 1, also known as Drosophila Delta homolog 1, H-Delta-1, and DLL1, is a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains. DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. DLL1 acts as a ligand for Notch receptors. DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. The Notch pathway is an evolutionary conserved intercellular signaling pathway involved in numerous biological processes including cell fate determination, cellular differentiation, proliferation, survival, and apoptosis. In mammalian cells, five Notch ligands (Jagged1, 2, DLL1, DLL3, DLL4) and four Notch receptors (Notch 1-4) have been identified, and ligand-receptor interactions results in proteolysis and translocation of the Notch intracellular domain. Analysis of DLL1 mutants reveals that it is necessary and sufficient to maintain a pool of progenitors in the embryonic neuroepithelium. DLL1 serves to prevent the untimely differentiation of neural progenitors. DLL1 also contributes to the control of proliferation and differentiation in (Interfollicular Epidermis) IFE.
DLL1抗体相关产品如下：
hz-15425R HCE5’-三磷酸聚核苷酸抗体
hz-10228R HINT1组氨酸三聚体核苷结合蛋白1抗体
hz-15426R hCG alpha 4甲状腺促进激素alpha链
hz-10298R H7N9 NAA型流感病毒H7N9凝集素抗体
hz-10024R HDAC3/HD3组蛋白去乙酰化酶3抗体
hz-1557G HBsAg人乙肝表面抗原抗体（包被）
hz-2713R HAVCR1肾损伤分子1抗体（甲型肝炎病毒细胞受体1）
hz-6052R HPRG组氨酸富含脯氨酸糖蛋白抗体
hz-2897R HER3HER3受体抗体
hz-3218R Phospho-HER3 (Tyr1197)磷酸化HER3受体抗体
hz-3219R Phospho-HER3 (Tyr1222)磷酸化HER3受体抗体
hz-3220R Phospho-HER4 (Tyr1284)磷酸化HER4抗体
hz-6053R Hemopexin糖蛋白β-1B抗体
hz-3225R Phospho-HSP27 (Ser15)磷酸化热休克蛋白27抗体
hz-15442R HEATR7AHEAT重复内含蛋白7A蛋白抗体
hz-0714R HPV16 E7人乳头瘤病毒16型E7抗体
hz-0125R HER2HER2抗体
hz-2902R HPL人胎盘泌乳素抗体
hz-0730R HSP27热休克蛋白27抗体
hz-1030R HMGA1高迁移率族蛋白A1抗体
hz-4004R Phospho-HER2 (Thr686)磷酸化HER2受体抗体
hz-1688R HSP20热休克蛋白-20抗体
hz-0464R Hydroxyethyk starch羟乙基淀粉抗体
hz-0422R H1N1 Matrix Protein 2A型流感病毒H1N1-M2蛋白抗体
hz-9067R HIP12亨丁顿舞蹈症相互作用蛋白12抗体
hz-10489R HHV11 DNA polymerase catalytic subunit单纯疱疹病毒1型DNA聚合酶催化亚单位抗体
hzm-2000M HBcAg(1H8)人乙型肝炎核心抗原单克隆抗体
hz-3179R Phospho-HSP27(Ser78)磷酸化热休克蛋白27抗体
hz-0899R His tag(CT)聚组氨酸抗体g标签抗体（C端）
hz-1737R phospho-Histone H1.4 (Ser27)磷酸化组蛋白H1,4样蛋白抗体
hz-2048R HER2 receptorHER2受体抗体
hz-1691R HCN4环化核苷酸调控阳离子通道蛋白亚型4
hz-15443R HEATR8HEAT重复内含蛋白8蛋白抗体
hz-9070R HN1L雄激素调节样蛋白抗体
hz-9069R HN1雄激素调节蛋白2抗体
hz-9703R S100A18角化蛋白S100A18抗体
hz-4857R Hepatitis C Virus NS4B丙型肝炎病毒NS4B抗体
hz-6459R HNRPC异质性核糖核蛋白C1/C2抗体
hz-6979R hnRNP R异质性核糖核蛋白R
hz-7612R HIPK4同源相互作用蛋白激酶4抗体
hz-9843R HCF2肝素辅助因子II抗体
hz-3530R HIRA组蛋白替换精蛋白DGGR1抗体
hz-15412R HAPLN4透明质酸及粘蛋白4抗体
hz-11348R Hippocalcin神经细胞特异性钙结合蛋白抗体
hz-8507R Hairless无毛发蛋白抗体
hz-6935R HAND2心脏和神经嵴衍生蛋白2抗体
hz-4707R Acetyl-Histone H4(K16)乙酰化组蛋白H4(K16)抗体
hz-0750R HLA G人类白细胞抗原G抗体（N端）