Carboxypeptidase A1 / CPA1抗体

Carboxypeptidase A1 / CPA1抗体产品信息

免疫原 :
Recombinant Mouse Carboxypeptidase A1 / CPA1 protein (Catalog#50448-M08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
003
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carboxypeptidase A1 / CPA1 (rM Carboxypeptidase A1 / CPA1; Catalog#50448-M08H; NP_079626.2; Met 1-Tyr 419).
Carboxypeptidase A1 / CPA1抗体Background
Carboxypeptidase A1 (CPA1) is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of pancreatic procarboxypeptidase A have been isolated.
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