KLK4 / Kallikrein 4抗体

KLK4 / Kallikrein 4抗体产品信息

免疫原 :
Recombinant Human KLK4 / Kallikrein 4 protein (Catalog#11857-H08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
104
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Human KLK4 / Kallikrein 4 (rh KLK4 / Kallikrein 4; Catalog#11857-H08H; NP_004908.3; Met1-Ser254).
KLK4 / Kallikrein 4抗体 Background
Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17 and EMSP1, is a secreted protein which belongs to thepeptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transition- and maturation-stage ameloblasts. KLK4 aggressively degrades the retained organic matrix following the termination of enamel protein secretion. Two proteases are secreted into the enamel matrix of developing teeth. The early protease is enamelysin (MMP-20). The late protease is kallikrein 4 (KLK4). The principle functions of MMP-20 and KLK4 in dental enamel formation are to facilitate the orderly replacement of organic matrix with mineral, generating an enamel layer that is harder, less porous, and unstained by retained enamel proteins. Defects in Kallikrein-4 / KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) which is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions.
KLK4 / Kallikrein 4抗体相关产品如下：
hz-13394R Glutaredoxin 2谷氧还蛋白2抗体
hz-13395R Glutaredoxin 5谷氧还蛋白5抗体
hz-13396R GPX2谷胱甘肽过氧化酶2抗体
hz-13397R GPX7谷胱甘肽过氧化酶7抗体
hz-13398R GSTA1谷胱甘肽S转移酶α1抗体
hz-13399R GSTK1谷胱甘肽S转移酶κ抗体
hz-3983R Galactose kinase半乳糖激酶1抗体
hz-3991R GYG2糖原蛋白2抗体
hz-3984R GALT磷酸半乳糖尿苷酸转移酶1抗体
hz-3990R GYG1糖原蛋白1抗体
hz-3989R Glycogen synthase 2葡萄糖合成酶2抗体
hz-3985R GOT2谷草转氨酶2抗体
hz-3987R Glucose 6 Phosphate Dehydrogenase葡萄糖-6磷酸脱氢酶抗体
hz-3988R GLUT5葡萄糖转运蛋白5抗体
hz-2359R Glycogen葡萄糖合成酶1抗体
hz-13502R GPATCH8G蛋白修补结构域蛋白8抗体
hz-13368R GK3甘油激酶3抗体
hz-13489R GOLPH3L高尔基体磷蛋白3样蛋白抗体
hz-8446R phospho-GluR1 (Ser849)磷酸化谷氨酸受体1抗体
hz-13498R GPATCH1/ECGPG蛋白修补结构域蛋白1抗体
hz-5374R phospho-GIT1(Tyr510) 磷酸化G蛋白偶联受体激酶相互作用蛋白1抗体
hz-5373R phospho-GIT1(Tyr554) 磷酸化G蛋白偶联受体激酶相互作用蛋白1
hz-2356R GKRP葡萄糖激酶调节蛋白抗体
hz-3893R GTPBP10GTP结合蛋白10抗体
hz-5376R phospho-G3BP1(Ser232)磷酸化Ras GTP酶活化蛋白结合蛋白1抗体
hz-4111R G3BP1Ras GTP酶活化蛋白结合蛋白1抗体
hz-4112R GABA A Receptor gamma 2γ氨基丁酸γ2受体/GABAA Rγ2抗体
hz-5367R phospho-GSK-3 Beta(Ser21+Ser29)磷酸化糖原合酶激酶3β抗体
hz-5372R phospho-GIT1(Ser375)磷酸化G蛋白偶联受体激酶相互作用蛋白1抗体
hz-5369R phospho-GATA1(ser142)磷酸化珠蛋白转录因子1抗体
hz-5370R phospho-GATA1(ser310)磷酸化珠蛋白转录因子1抗体
hz-4110R GIT1G蛋白偶联受体激酶相互作用蛋白1抗体
hz-5375R phospho-GATA6(Tyr271)磷酸化GATA结合蛋白6抗体
hz-5377R phospho-GABRG2(Ser327)磷酸化γ氨基丁酸γ2受体/GABAA Rγ2抗体
hz-3945R Glucagon Receptor胰高血糖素受体抗体
hz-5099R GDF3生长分化因子3抗体
hz-5368R phospho-GSK-3 Beta(Ser21)磷酸化糖原合酶激酶3β抗体
hz-12019R GPR1G蛋白偶联受体1抗体
hz-3941R G protein beta 1G蛋白β1抗体/鸟嘌呤核苷酸结合蛋白β亚基1
hz-3943R G protein beta 3G蛋白β3抗体/鸟嘌呤核苷酸结合蛋白β亚基3
hz-13463R GMPR2鸟苷酸还原酶2抗体
hz-13242R G gamma12G蛋白偶联受体γ12抗体
hz-6164R GRAP2生长因子受体结合蛋白2相关接头蛋白2抗体
hz-6152R GNAQG蛋白α亚单位蛋白Q抗体
hz-5904R GADD45B生长抑制DNA损伤基因GADD45β抗体
hz-6227R GIG22细胞生长抑制蛋白22抗体（甲基化控制J蛋白）
hz-5789R GPR39G蛋白偶联受体39抗体
hz-6644R Gephyrin桥尾蛋白抗体
hz-5839R Galectin 8半乳糖凝集素8抗体
hz-7801R GPIP137糖磷脂酰肌醇锚定蛋白137抗体
hz-7800R GLP2R胰高血糖素样肽2受体抗体
hz-6385R Gas1生长休止特定蛋白1抗体
hz-13352R GGTL1γ-谷氨酰转移酶轻链1抗体
hz-6708R GABRA5γ1氨基丁酸受体α5/GABRα5抗体
hz-6672R GIRK1G蛋白激活内向钾通道1抗体
hz-6673R GIRK3G蛋白激活内向钾通道3抗体
hz-6676R GPR48G蛋白偶联受体48抗体