CRP / C-Reactive Protein抗体

CRP / C-Reactive Protein抗体产品信息

免疫原 :
Recombinant Mouse CRP / C-Reactive Protein protein (Catalog#50409-M08H)
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 :
132
抗体宿主 :
Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 :
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CRP / C-Reactive Protein (rM CRP / C-Reactive Protein; Catalog#50409-M08H; NP_031794.3; Met1-Ser225).
CRP / C-Reactive Protein抗体 Background
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of C-Reactive Protein/CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum C-Reactive Protein/CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, C-Reactive Protein/CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. C-Reactive Protein/CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased C-Reactive Protein/CRP production and coronary atherothrombotic events is of particular interest.
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