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文献和实验Analysis of Human FOXP3+ Treg Cells Phenotype and Function
-cell level and to uncover the functional heterogeneity that exists among the CD4+ FOXP3+ T Reg cell population in human PBMC.
Isolation of a Purified Epithelial Cell Population from Human Colon
. For the human colon, isolation techniques to allow direct study have been described for mononuclear cells in the lamina propria, smooth muscle cells at or below the muscularis mucosae, and cells of the enteric nervous system, located between the subserosa
. Mice and human with Foxp3 mutations are severely impaired in Treg cell generation and develop lethal autoimmune diseases. We combined chromatin immuno-precipitation and mouse whole genome tiling array profiling (ChIP-on-Chip) to identify the direct
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