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- 保存条件:
常温,避光
- 克隆性:
单克隆
- 抗体名:
CA12 / CAXII / Car12抗体
Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, human cell-derived, recombinant human CA12 extracellular domain ( rh CA12 ; Catalog#10617-H08H ; NP_001209.1 ; Met 1 - Gln 291 ). CA12 specific IgG was purified by human CA12 affinity chromatography.
CA12 / CAXII / Car12抗体 Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. This bitopic membrane protein contains an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. Two alternatively spliced forms exist, which either contains or lacks a 11 amino acid segment just before the transmembrane domain. The structure reveals a prototypical CA fold and two CA XII domains associate to form an isologous dimer. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker.
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文献和实验,可通过绘制标准曲线求出标本中E2F1 浓度。 试剂盒组成 ( 2-8 ℃保存) 酶标 板 (Coated Wells ) 96 孔 酶标抗体工作液(Enzyme Conjugate ) 12ml
盘点 2020 年中国学者的十大免疫学研究成果,有的已经被写进高考题?!
,而且抑制免疫细胞、促进癌细胞生长砷剂疗法的前世今生:「吃最毒的药,治最难的病」,「砒霜」抗癌再登 Cell 子刊参考文献:1.Y. Liu et al., Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome. Sci Immunol 5, (2020).2.X. Wang et al., Febrile Temperature Critically Controls
。 1)双向开关功能: X1-X2:single、double 单排或双排洗头。 X8-X12:8way、12way 8通道或12通道洗头。 plate(板)-strit(条): 板模式或条模式。 step off-step over:step off是在洗完最后一排后回到预洗位置,而step over则否。 wet(湿)-dry(干): 洗完后是保存洗板还是干板。板模式中,全部洗完后逐排洗干。条模式中,每洗完一排即吸干。 F1关-final ×1和F2关-final ×
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