Epcr / PROCR抗体

Epcr / PROCR抗体产品信息免疫原 : Recombinant Mouse Epcr / PROCR protein (Catalog#50874-M08H)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Mouse Epcr / PROCR (rM Epcr / PROCR; Catalog#50874-M08H; Q64695; Met 1-Ser 214). Total IgG was purified by Protein A affinity chromatography.
Epcr / PROCR抗体 Background
Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found maily near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depend on whether or not protein C remains bind to EPCR after activated. The anticoagulation occur when it does not. When still bound to EPCR, activated protein C performs its cytoprotective effects.
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