CABP3 / CABP5抗体

CABP3 / CABP5抗体产品信息免疫原 : Recombinant Human CABP3 / CABP5 protein (Catalog#13896-H07E)

Antibody Type : Rabbit Polyclonal Antibody ( Antibody Purification Platform )
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : Produced in rabbits immunized with purified, recombinant Human CABP3 / CABP5 (rh CABP3 / CABP5; Catalog#13896-H07E; Q9NP86; Met1-Arg173). Total IgG was purified by Protein A affinity chromatography.
CABP3 / CABP5抗体 Background
CABP3, also known as CABP5, is a member of the subfamily of calcium binding proteins. Calcium-binding proteins share similarity to calmodulin and participate in calcium cell signalling pathways by binding to Ca2+. Calcium-binding proteins play a key role in signal transduction and they also contribute to all aspects of the cell's functioning, from homeostasis to learning and memory. It has been shown that the mouse homolog of CABP3 express in the inner nuclear layer of the retina, suggested its role in neuronal functioning. CABP3 inhibits calcium-dependent inactivation of L-type calcium channel and shifts voltage dependence of activation to more depolarized membrane potentials. It is also involved in the transmission of light signals. Expression of this CABP3 is retina-specific. The specific function of this gene is unknown. CABP5 and CABP3 genes encode the protein products with distinct N-terminal halves but identical C-terminal halves.
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