HGF / Hepatocyte Growth Factor

HGF / Hepatocyte Growth Factor抗体产品信息免疫原 : Recombinant Human HGF / Hepatocyte Growth Factor protein (Catalog#10463-H08H)

Antibody Type : Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
克隆号 : 04

抗体宿主 : Mouse IgG1
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HGF / Hepatocyte Growth Factor (rh HGF / Hepatocyte Growth Factor; Catalog#10463-H08H; NP_000592.3; Met 1-Ser 728). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
HGF / Hepatocyte Growth Factor抗体 Background
Hepatocyte growth factor (HGF), also known as Scatter factor, is a paracrine cellular growth, motility and morphogenic factor. Hepatocyte Growth Factor/HGF is a member of the peptidase S1 family, and is derived from a single chain precursor of 728 amino acid residues containing 4 kringle domains, 1PAN domain and 1peptidase S1 domain. The synthesized single chain of HGF is further processed into a bioactive heterodimer composed of the 69 kDa α-subunit and the 34 kDa β-subunit by a serine protease. Hepatocyte Growth Factor/HGF has no detectable protease activity. Alternative splicing of its gene produces multiple transcript variants encoding different isoforms. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, as well as haemopoietic progenitor cells. Hepatocyte Growth Factor/HGF regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the c-Met receptor. Hepatocyte Growth Factor/HGF may also play an important role as a paracrine or endocrine mediator through an epithelial-mesenchymal interaction in wound-healing, tissue or organ regeneration, morphogenesis and carcinogenesis.
HGF / Hepatocyte Growth Factor抗体相关产品如下：xy-11847R GPM6B神经细胞膜糖蛋白M6b
xy-6247R GUK1鸟苷酸激酶GMK抗体
xy-4691R Galactocerebroside半乳糖脑苷脂酶抗体
xy-7540R GRK5G蛋白偶联受体激酶5抗体
xy-7502R GTP binding protein REM1GTP结合蛋白REM1抗体
xy-4692R phospho-GSK3 Alpha(Ser21)磷酸化糖原合酶激酶-3α抗体
xy-11461R GDF7生长分化因子7抗体
xy-7057R Glucokinase regulatory protein葡萄糖激酶调节蛋白抗体
xy-8402R GCLCγ谷氨酰半胱氨酸合成酶抗体（γ-GCSc）
xy-8403R GCOM1GCOM1蛋白抗体
xy-8405R GFOD2葡萄糖果糖还原酶2抗体
xy-8406R GFRAL胶质细胞系源性神经营养因子受体α1样蛋白抗体
xy-8407R GHDCGHDC蛋白抗体
xy-8408R GK5甘油激酶5抗体
xy-8409R GLB1L3β半乳糖苷酶1样蛋白3抗体
xy-8410R GLCCI1糖皮质激素诱导转录蛋白1抗体
xy-8411R GLIPR2脑胶质瘤发病相关蛋白2抗体
xy-11725R GDAP1神经节苷脂诱导分化相关蛋白1抗体
xy-12015R GPR18G蛋白偶联受体18抗体
xy-12016R GPR119G蛋白偶联受体119抗体
xy-12017R GPR88G蛋白偶联受体88抗体
xy-12021R GPR125G蛋白偶联受体125抗体
xy-12006R GRIK2谷氨酸受体红藻氨酸离子2/谷氨酸受体6抗体
xy-12007R GRIK3谷氨酸受体红藻氨酸离子3/谷氨酸受体7抗体
xy-12008R GRIK2 + GRIK3谷氨酸受体红藻氨酸离子2/3抗体
xy-12009R GluA4离子型谷氨酸受体4抗体
xy-12010R phospho-GluA4 (Ser862)磷酸化离子型谷氨酸受体4抗体
xy-12011R GRM1代谢型谷氨酸受体1A抗体
xy-7791R CKS2细胞周期蛋白依赖性激酶调节亚基2抗体
xy-11727R GRK3β肾上腺素能受体激酶2抗体
xy-12003R GNAL腺苷酸环化酶Gα蛋白/Gαs/olf抗体
xy-7912R GAK protein细胞周期蛋白G相关激酶抗体
xy-9555R GLT8D1糖基转移酶8结构域1抗体
xy-9432R RNF27环指蛋白27抗体
xy-11263R GC1q R透明质酸结合蛋白1抗体
xy-11235R GRK6G蛋白偶联受体激酶6抗体
xy-11248R GRAF1 Rho GTP酶激活蛋白26抗体