CLEC4N / Dectin-2抗体

CLEC4N / Dectin-2抗体产品信息免疫原 : Recombinant mouse CLEC4N protein ( Catalog#50267-M08H )

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 : 1
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant mouse CLEC4N extracellular domain ( rM CLEC4N ; Catalog#50267-M08H ; NP_064385.1 ; Ile 44 - Leu 209 ).
CLEC4N / Dectin-2抗体背景综述
Mouse C-type lectin domain family 4 member N, also known as CLEC4N, is a 209 amino acid (aa) protein and contains one C-type lectin domain. Members of the C-type lectin domain (CTLD) superfamily are metazoan proteins functionally important in glycoprotein metabolism, mechanisms of multicellular integration and immunity. They share a common fold and are involved in a variety of functions, such as generalized defense mechanisms against foreign agents, discrimination between healthy and pathogen-infected cells, and endocytosis and blood coagulation. Genome-level studies on human, elegans and melanogaster demonstrated almost complete divergence among invertebrate and mammalian families of CTLD-containing proteins (CTLDcps). The vertebrate CTLDcp family was essentially formed early in vertebrate evolution and is completely different from the invertebrate families. The composition of the CTLDcp superfamily in fish and mammals suggests that large scale duplication events played an important role in the evolution of vertebrates.
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