IL1RL1 / IL1R4抗体

IL1RL1 / IL1R4抗体产品信息免疫原 : Recombinant Human IL1RL1 / IL1R4 Protein (Catalog#10105-H08H)

Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 : 003
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant Human IL1RL1 / IL1R4 ( rh IL1RL1 / IL1R4; Catalog#10105-H08H; Met 1 - Phe 328; NP_003847.2)
IL1RL1 / IL1R4抗体 Background
The protein IL1 RL1, also known as T1, ST2, is a member of the interleukin-1 receptor family with a soluble secreted form (sST2) and a transmembrane form (ST2L). The coding gene forms a cytokine receptor gene cluster together with IL1R1(interleukin 1 receptor, type I), IL1R2(interleukin 1 receptor, type I I) and IL1RL2(interleukin 1 receptor-like 2) genes in a region mapped to chromosome 2q12. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of the protein IL1RL1 and induces production of Th2 cytokines.
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