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- 中国/美国/德国
- xy11019-R101
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
常温，避光
- 克隆性：
单克隆
- 抗体名：
Transferrin / TF抗体
Antibody Type : Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
克隆号 : 101
抗体宿主 : Rabbit IgG
缓冲液 : 0.2 μm filtered solution in PBS, 5% trehalose may be added in some batches. Please read the hardcopy of COA or contact our customer service to confirm the formulation.
制备方法 : This antibody was obtained from a rabbit immunized with purified, recombinant Human Transferrin / TF (rh Transferrin / TF; Catalog#11019-H08H; NP_001054.1; Met 1-Pro 698).
Transferrin / TF抗体 Background
Transferrin, also known as Serotransferrin, Beta-1 metal-binding globulin, TF, is a secreted protein which belongs to thetransferrin family. It is expressed by the liver and secreted in plasma and contains two transferrin-like domains. Transferrins are iron binding transport proteins which can bind two Fe3+ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. When a transferrin protein loaded with iron encounters atransferrin receptoron the surface of acell, it binds to it and, as a consequence, is transported into the cell in avesicle. Transferrin is aglycoproteinthat binds iron very tightly but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of the total body iron, it is the most important iron pool, with the highest rate of turnover (25 mg/24 h). Defects in transferrin are the cause of a transferrinemia (ATRAF) which is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Transferrin is also associated with the innate immune system.
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文献和实验Arachidonic Acid Labeling 花生死烯酸标记方法
serum free media and supplement with ITS (4 ml/L should yield 5 mg/L insulin and 5 mg/L transferrin).--> "Appropriate" = bring cells to a final concentration of 5 X 105 cells/ml.4) Add [3H] arachidonic acid to get ~2 µCi/ml (2 X 106 µCi/ml???).--> Make
with ITS (4 ml/L should yield 5 mg/L insulin and 5 mg/L transferrin). --> "Appropriate" = bring cells to a final concentration of 5 X 105 cells/ml. 4) Add [3H] arachidonic acid to get ~2 µCi/ml (2 X 106 µCi/ml???). --> Make sure final AA
with ITS (4 ml/L should yield 5 mg/L insulin and 5 mg/L transferrin). --> "Appropriate" = bring cells to a final concentration of 5 X 105 cells/ml. 4) Add [3H] arachidonic acid to get ~2 µCi/ml (2 X 106 µCi/ml???). --> Make sure final AA
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