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北京盛科博源生物科技有限公司
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文献和实验PEGPEI Copolymers for Oligonucleotide Delivery to Cells and Tissues
compounds that markedly improve the in vitro and in vivo delivery of AOs to cells and tissues. By varying the Mw of PEI, as well as the nature of PEG shielding, PEG-PEI-AO nanoparticulates can be prepared with a dynamic range of size, surface charge
in the hydroxide (OH-) form and the cation-exchange resin in the acid (H+) form. Anions or cations in the water (including monovalent) are exchanged for OH-or H+, respectively, which combine to form neutral water. Any imbalance in the removal of the ions can result
in the hydroxide (OH-) form and the cation-exchange resin in the acid (H+) form. Anions or cations in the water (including monovalent) are exchanged for OH-or H+, respectively, which combine to form neutral water. Any imbalance in the removal of the ions can result
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