LAG-3/CD223 Antibody
Cat#:PL0303815
Isotype:Rabbit Polyclonal IgG
Immunogen:Peptide derived from human LAG-3 C-terminus.
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
Alternate Names:
Lymphocyte activation gene 3; CD223; FDC protein; LAG 3; LAG3; Lymphocyte activation gene 3 protein; LAG3_HUMAN.
Specificity Reaction:Hu, Mo, Rat, Pig, Cow, Hor,
Application Notes:WB: 1:100-500 E: 1:500-1000 IP: 1:20-100 IHC: 1:100-500 FC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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