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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within human B-raf.
- 亚型:
Chicken Ig
- 形态:
Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 宿主:
Chicken
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
B-raf
- 抗体英文名:
B-raf Antibody
- 抗体名:
B-raf Antibody
- 规格:
0.1 mg
B-raf Antibody产品详细介绍:
| 产品名称: | B-raf Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 254293 |
| 规格: | 0.1 mg |
| 产品描述: | B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance. |
| 克隆类型: | Chicken Polyclonal Antibody |
| 亚型: | Chicken Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within human B-raf. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名: | B-raf; v-raf murine sarcoma viral oncogene homolog B1; proto-oncogene B-raf; p94 |
| 形态: | Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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文献和实验Monitoring Oncogenic B-RAF-Induced Senescence in Melanocytes
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