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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体英文名:
Proteinase Inhibitor 9 (PI9) Antibody,CAP3 CAP3 Cytoplasmic antiase3 PI9 Protease inhibitor9 ovalbumin type Serpin B9 Serine or Cysteine ase Inhibitor
- 规格:
100 ug
产品名称:Proteinase Inhibitor 9 (PI9)抗体 |Proteinase Inhibitor 9 (PI9) Antibody,CAP3 CAP3 Cytoplasmic antiase3 PI9 Protease inhibitor9 ovalbumin type Serpin B9 Serine or Cysteine ase Inhibitor
【产品形式】:艾美捷为您提供的Proteinase Inhibitor 9 (PI9)抗体 产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有50%甘油, 1% BSA和0.02%硫柳汞的PBS缓冲液中.请将该Proteinase Inhibitor 9 (PI9)抗体 产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.
【背景资料】:Proteinase inhibitor 9 (PI-9, also designated cytoplasmic antiproteinase 3, or CAP3) is a 42 kDa member of the ovalbumin family of serpins that is expressed in placenta, lung and cytotoxic lymphocytes. PI-9 is a potent inhibitor of granzyme B and of granzyme B-mediated apoptosis, and is also an inhibitor of capase-1 and, to a smaller extent, caspase-4 and caspase-8. PI-9 expression is also upregulated in response to inflammatory stimuli. This upregulation protects cells from apoptosis induced by endogenously expressed or released granzyme B, particulary during target cell killling.
BioVision的公司总部在美丽的旧金山湾地区,它是全球生命科学公司的领导者.BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有 卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品,以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代 谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理, 艾美捷与BioVision一起为研究者们提供最好、最新的细胞生物学研究工具而不断扩大产品及服务质量.
点击:Proteinase Inhibitor 9 (PI9)抗体 ,查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询BioVision中国区域授权总代理艾美捷科技有限公司。
关键词:Proteinase Inhibitor ,Proteinase Inhibitor 9 (PI9)抗体
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文献和实验Expression of Recombinant Proteinase Inhibitors in Plants
), emphysema (25 ), pancreatitis (26 ), and AIDS (27 ,28 ). Table 1 PI-Expressing Transgenic Plants: Some Examples a Plant Inhibitor
Combined 3C-ChIP-Cloning (6C) Assay: A Tool to Unravel Protein-Mediated Genome Architecture
:chloroform:isoamyl alcohol, UltraPure (25:24:1 v/v/v; Invitrogen) Phosphate-buffered saline (PBS; GIBCO 20012) Protease inhibitor cocktail (Sigma P8340) Proteinase K (10 mg/mL in TE buffer, pH 8.0; Invitrogen) PureLink HQ 96 Mini
的启动子和终止子,“i”代表inhibitor其结构也可简化为:首先讲下阻碍蛋白的调控原理:当培养基中无乳糖时,阻碍蛋白与操纵子O结合,阻断了RNA聚合酶与启动子P的进一步反应。而IPTG能与阻碍蛋白结合,使转录反应进一步发生CAP的调控原理:可加强转录活性,细菌才能合成足够的酶来利用乳糖葡萄糖→ →降解产物(能抑制腺苷酸环化酶活性)ATP → →cAMP(需腺苷酸环化酶)上述两个反应导致:葡萄糖存在时,cAMP浓度低;仅在葡萄糖消耗完毕时, cAMP浓度增高,CAP-cAMP 复合物形成(结合
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