二泛素蛋白 (Ub2, K11-linked) | Di-u

【产品形式】：艾美捷为您提供的二泛素蛋白 (Ub2, K11-linked)形式为50mM Tris-Cl, pH7.5, 100mM NaCl, 1mM DTT

【背景资料】：Di-ubiquitin (Ub2, K11-linked) was synthesised enzymatically using wild type ubiquitin, purified by FPLC and K11 only linkage confirmed by mass spectrometry following tryptic digest. Specifically linked di-ubiquitins have utility as substrates for investigating deubiquitinating enzyme (DUB) activity and polyubiquitin chain processing selectivity and in the study of ubiquitin binding and recognition in ubiquitin signalling associated processes. K11-linked polyubiquitin molecules are thought to be efficient signals for proteasomal degradation and are utilised by the human anaphase-promoting complex (APC/C) and associated DUBs in the regulation of cell cycle progression. Modification of cellular proteins with polyubiquitin chains occurs in a wide range of signalling pathways and is tightly regulated in order to ensure cellular homeostasis. The function, processing and ultimate fate of polyubiquitinylated proteins is thought to be determined by the nature of the linkage between adjacent ubiquitin molecules in the polyubiquitin chain.

英国Viva Bioscience公司是一家研发、生产并销售蛋白降解相关产品的公司。其产品主要用于细胞自噬、泛素化和蛋白酶体研究（也覆盖其他蛋白降解相关的产品），其产品价格合理、质量可靠且具有创新性。目前VIVA Bioscience提供逾460种产品，涉及细胞自噬、蛋白泛素化和讲解相关的所有试剂盒、蛋白、底物以及多种抑制剂、激活剂等全系列产品。作为多家进口品牌的中国区域总代理，艾美捷科技与Viva Bioscience一道为中国科研工作者们提供更好、更新的自噬、泛素化和蛋白酶体等研究工具。

点击二泛素蛋白 (Ub2, K11-linked)查看更详细产品说明，更多应用、储存、价格、货期等信息请致电垂询Viva Bioscience中国区域授权总代理艾美捷科技有限公司。