帕金蛋白抗体

帕金蛋白抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

帕金蛋白抗体产品介绍

parkin基因的突变，患者很早就会出现帕金森氏症的症状，Parkin属于RBR蛋白家族，与泛素相关蛋白分解途径有关。
Parkinson's Disease, the second most common neurodegenerative disease after Alzheimer's Disease, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions). Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin. Parkin, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation. The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, thus targeting them for degradation by the proteasome.xy-15568R IGF2ASIGF2基因的互补基因1蛋白抗体
xy-15551R IFI44L干扰素诱导蛋白44样蛋白抗体
xy-10028R ITGB4整合素β4抗体
xy-15575R IGKV A18kappa轻链可变区抗体
xy-2583R ICOS/CD278诱导协同刺激分子CD278抗体
xy-2630R IL-31白细胞介素31抗体
xy-2627R IL-28A/IFNL2白细胞介素28A抗体
xy-2632R IL-32/NK4白介素32抗体
xy-2633R IL-33/NFHEV白介素33抗体
xy-2634R ILT2/CD85j细胞表面免疫球蛋白样转录因子2抗体
xy-2635R Integrin alpha 2/CD49b整合素α2抗体
xy-2636R Integrin alpha 2b/CD41血小板膜糖蛋白ⅡbⅢa抗体
xy-2607R IL-17RC/IL-17RL白介素17受体C抗体
xy-2584R IGSF8免疫球蛋超家族成员8抗体
xy-2208R IL-33白介素33抗体
xy-7715R Importin 9核蛋白9抗体（Ran结合蛋白M）
xy-3840R eIF3A真核翻译起始因子3A抗体
xy-4003R phospho-eIF4G (ser1185)磷酸化真核翻译起始因子4G抗体
xy-2055R Integrin alpha 4+Beta 7整合素α4β7抗体
xy-9278R phospho-IRF3 (Ser386)磷酸化干扰素调节因子3抗体
xy-9025R ISLR2ISLR2蛋白抗体
xy-9022R IQCGIQCG蛋白抗体
xy-9023R IQCKIQCK蛋白抗体
xy-6541R Id1DNA结合抑制因子1抗体
xy-6256R IMPDH1肌苷单磷酸脱氢酶1抗体
xy-6653R IFI78干扰素诱导蛋白P78抗体
xy-6686R ICAM5细胞间粘附分子5抗体
xy-6248R IMPAD1肌醇单磷酸酶IMPA3抗体
xy-5791R Integrin Alpha V + Beta 6整合素αVβ6抗体
帕金蛋白抗体