抗磷酸化Fas死亡结构域相关蛋白抗体

抗磷酸化Fas死亡结构域相关蛋白抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

抗磷酸化Fas死亡结构域相关蛋白抗体产品说明

FADD (Fas Associated Death Domain) is an apoptosis adapter molecule enabling transduction of the apoptosis signal initiated via the FasL/Fas receptor interaction. The protein contains a C terminal death domain that interacts with the Fas receptor death domain. The N terminus contains a death effectors domain (DED) which recruits caspase to the death inducing signaling complex (DISC) and initiates the apoptotic caspase cascade. Recruitment of Caspase 8 to the Fas receptor results in oligomerization of the Caspase 8 protein, which in turn drives its autoactivation through self-cleavage. Activated Caspase 8 then activates other downstream caspases including Caspase 9, thereby commiting the cell to undergo apoptosis. FADD is implicated in non-apoptotic cellular pathways such as the regulation of cell cycle machinery in T lymphocytes. This is connected to the phosphorylation state of FADD and to the FasL/TRAIL induced transcriptional activation of cfos protooncogene. FADD also interacts with the hepatitis C virus core protein in the HEK 293 cell line.
Also known as:
P-Fas-associated protein with death domain; FADD protein; Fas (TNFRSF6) associated via death domain; Fas associated via death domain; Fas associating death domain containing protein; Fas associating protein; Fas associating protein with death domain; Fas TNFRSF6 associated via death domain; GIG 3; GIG3; Growth inhibiting gene 3 protein; H sapiens mRNA for mediator of receptor induced toxicity; Mediator of receptor induced toxicity ; MGC8528 ; MORT 1; MORT1

xy-9289R PACRG麻疯病和帕金森氏病共同调节蛋白抗体
xy-9290R RNF131环指蛋白131抗体
xy-3807R Phospholipase A2 activator protein磷脂酶A2激活蛋白抗体
xy-3809R thymidine phosphorylase胸苷磷酸化酶抗体
xy-3817R Piwil2piwi样2蛋白抗体
xy-3815R presenilin 2早老素蛋白-2抗体
xy-8176R PHF8组蛋白赖氨酸去甲基化酶PHF8抗体
xy-9363R TRAP2肿瘤坏死因子受体相关蛋白2抗体
xy-9366R PSMD7蛋白酶调解因子7抗体
xy-2215R phosphos-PCNA (Tyr211)磷酸化增殖细胞核抗原抗体
xy-3027R phospho-AMPK beta 1 (Ser182)磷酸化腺苷单磷酸活化蛋白激酶β1抗体
xy-4033R PDHB丙酮酸脱氢酶E1β亚单位抗体
xy-4032R PHKB磷酸化酶β抗体
xy-4030R Pancreatic Amylase胰淀粉酶抗体
xy-4034R PDHA1丙酮酸脱氢酶α1抗体
xy-4036R phospho-PDHA1(Ser293)磷酸化丙酮酸脱氢酶α1抗体
xy-2739R PDPK13磷酸肌醇依赖性蛋白激酶1抗体
xy-3017R Phospho-PDPK1(Tyr373 + Tyr376)磷酸化3磷酸肌醇依赖性蛋白激酶1抗体
xy-2740R p53BP1p53结合蛋白1抗体
xy-3726R phospho-PKC delta (Tyr52)磷酸化蛋白激酶C亚性D型抗体
xy-3727R phospho-PKC delta (Thr505/507)磷酸化蛋白激酶C亚性D型抗体
xy-10399R PKC zeta蛋白激酶C zeta 抗体
xy-7340R PRG2嗜酸性粒细胞颗粒关键碱性蛋白抗体
xy-1664R Proinsulin胰岛素原抗体
xy-15501R PCSK4原蛋白转化酶4抗体
xy-4978R PMCA1细胞膜钙ATP酶1抗体
xy-4972R PCK1磷酸烯醇丙酮酸羧激酶抗体
xy-4966R PAPOA多聚合酶α抗体
抗磷酸化Fas死亡结构域相关蛋白抗体