Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM]
Rat (24805): component of synaptic vesicle membranes; may have important role in vesicle trafficking to the active zone of the synapse and in exocytosis; may be the crucial calcium sensor in neurotransmitter release [RGD] mol wt:46kDa
Other Aliases: Synaptotagmin II; SYNII; Syt2; RATSYNII; SYNII; FLJ42519; KIAA4194; LOC100127887; mKIAA4194; R74640; RATSYNII; SYNAPTOTAGMIN 2; SYT2; SytII